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ABHD1_BOVIN
ID   ABHD1_BOVIN             Reviewed;         404 AA.
AC   Q3T0A0;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Protein ABHD1 {ECO:0000305};
DE            EC=3.1.1.-;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 1 {ECO:0000305};
DE            Short=Abhydrolase domain-containing protein 1 {ECO:0000250|UniProtKB:Q96SE0};
GN   Name=ABHD1 {ECO:0000250|UniProtKB:Q96SE0};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC       family. {ECO:0000305}.
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DR   EMBL; BC102483; AAI02484.1; -; mRNA.
DR   RefSeq; NP_001030266.1; NM_001035094.2.
DR   AlphaFoldDB; Q3T0A0; -.
DR   STRING; 9913.ENSBTAP00000009303; -.
DR   ESTHER; bovin-abhd1; abh_upf0017.
DR   PaxDb; Q3T0A0; -.
DR   PRIDE; Q3T0A0; -.
DR   Ensembl; ENSBTAT00000009303; ENSBTAP00000009303; ENSBTAG00000007077.
DR   GeneID; 510774; -.
DR   KEGG; bta:510774; -.
DR   CTD; 84696; -.
DR   VEuPathDB; HostDB:ENSBTAG00000007077; -.
DR   VGNC; VGNC:25487; ABHD1.
DR   eggNOG; KOG1838; Eukaryota.
DR   GeneTree; ENSGT00950000182902; -.
DR   HOGENOM; CLU_032487_4_0_1; -.
DR   InParanoid; Q3T0A0; -.
DR   OMA; NYCGEEG; -.
DR   OrthoDB; 1162019at2759; -.
DR   TreeFam; TF313195; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000007077; Expressed in abomasum and 102 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008126; F:acetylesterase activity; IBA:GO_Central.
DR   GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR   GO; GO:0034338; F:short-chain carboxylesterase activity; IBA:GO_Central.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR   GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0051793; P:medium-chain fatty acid catabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR012020; ABHD4.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Membrane; Reference proteome; Serine esterase; Signal-anchor;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..404
FT                   /note="Protein ABHD1"
FT                   /id="PRO_0000280203"
FT   TRANSMEM        17..37
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          122..363
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        202
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        328
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        357
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   404 AA;  44756 MW;  1A9C228930711896 CRC64;
     MLSSSQSPQD DTWTESFSLL LGLGAALYLG YYWTWVPQRP QLVTGSRFLA FLEQHCPVTL
     ETFYPTLWCF EGRLQTIFRV LLQSRPVVPY SSEVLETPDG GQILLDWASQ SNSQYPDPST
     QPTVLLLPGI TGSSQETYIL HLVDQALKDG YRAVVFNNRG CRGEELLTHR AFCASNTEDL
     VTVINHIKSR YPQAPLLAVG ISLGGILVLN HLARTGRAAG LVAALTLSAC WDSFETTRSL
     ETPLNSLLFN HRLTAGLCQV VNRNRKVMDN VVNVDFVLQA RTIREFDERY TAVVFGYQDC
     TAYYQAASPR TKVNAIQIPV LCLNAADDPF SPVDALPLQA AQHSLHVALL VTARGGHIGF
     LEGLLPWQHC YMSRLLHQYA EAIFQHPAEL PGPRSPTPSE AGKS
 
 
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