SOXD_ARTSP
ID SOXD_ARTSP Reviewed; 98 AA.
AC Q9AGP2;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=Sarcosine oxidase subunit delta;
DE Short=Sarcosine oxidase subunit D;
DE EC=1.5.3.1;
GN Name=soxD;
OS Arthrobacter sp.
OC Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX NCBI_TaxID=1667;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBUNIT.
RC STRAIN=1IN;
RX DOI=10.1007/BF00127888;
RA Meskys R., Rudomanskis R., Leipuviene R.;
RT "Cloning of genes encoding heterotetrameric sarcosine oxidase from
RT Arthrobacter sp.";
RL Biotechnol. Lett. 18:781-786(1996).
CC -!- FUNCTION: Catalyzes the oxidative demethylation of sarcosine to yield
CC glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate.
CC {ECO:0000269|Ref.1}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O2 + sarcosine = formaldehyde + glycine + H2O2;
CC Xref=Rhea:RHEA:13313, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:16240, ChEBI:CHEBI:16842, ChEBI:CHEBI:57305,
CC ChEBI:CHEBI:57433; EC=1.5.3.1;
CC -!- SUBUNIT: Heterotetramer (SoxA, SoxB, SoxG and SoxD).
CC {ECO:0000269|Ref.1}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR EMBL; AF329478; AAK16488.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9AGP2; -.
DR SMR; Q9AGP2; -.
DR PRIDE; Q9AGP2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.2270.10; -; 1.
DR InterPro; IPR006279; SoxD.
DR InterPro; IPR038561; SoxD_sf.
DR Pfam; PF04267; SoxD; 1.
DR TIGRFAMs; TIGR01374; soxD; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Oxidoreductase.
FT CHAIN 1..98
FT /note="Sarcosine oxidase subunit delta"
FT /id="PRO_0000428958"
SQ SEQUENCE 98 AA; 11273 MW; 04843A49A0FD1233 CRC64;
MMLIECPNCG PRNETEFSYG GQAHVAYPED PNTLSDKEWS RYLFYRGNSK GIFAERWVHS
GGCRKWFNAL RDTATYEFKA VYRAGEPRPE LNTQGGSR