ID   SOXD_CORS1              Reviewed;          98 AA.
AC   Q46336;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Sarcosine oxidase subunit delta;
DE            Short=Sarcosine oxidase subunit D;
DE            EC=1.5.3.1;
GN   Name=soxD;
OS   Corynebacterium sp. (strain P-1).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium; unclassified Corynebacterium.
OX   NCBI_TaxID=69006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-22.
RX   PubMed=7543100; DOI=10.1074/jbc.270.31.18252;
RA   Chlumsky L.J., Zhang L., Jorns M.S.;
RT   "Sequence analysis of sarcosine oxidase and nearby genes reveals homologies
RT   with key enzymes of folate one-carbon metabolism.";
RL   J. Biol. Chem. 270:18252-18259(1995).
CC   -!- FUNCTION: Catalyzes the oxidative demethylation of sarcosine to yield
CC       glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O2 + sarcosine = formaldehyde + glycine + H2O2;
CC         Xref=Rhea:RHEA:13313, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:16240, ChEBI:CHEBI:16842, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:57433; EC=1.5.3.1;
CC   -!- SUBUNIT: Heterotetramer (SoxA, SoxB, SoxG and SoxD).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U23955; AAC43460.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q46336; -.
DR   SMR; Q46336; -.
DR   KEGG; ag:AAC43460; -.
DR   BioCyc; MetaCyc:MON-8524; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.2270.10; -; 1.
DR   InterPro; IPR006279; SoxD.
DR   InterPro; IPR038561; SoxD_sf.
DR   Pfam; PF04267; SoxD; 1.
DR   TIGRFAMs; TIGR01374; soxD; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Oxidoreductase.
FT   CHAIN           1..98
FT                   /note="Sarcosine oxidase subunit delta"
FT                   /id="PRO_0000072049"
SQ   SEQUENCE   98 AA;  11315 MW;  0498563A3127BAD3 CRC64;
     MMLIECPNCG PRNETEFSYG GQAHVAYPED PNALSDKEWS RYLFYRENSK GIFAERWVHS
     GGCRKWFNAL RDTATYEFKA VYRAGEPRPE LNTQGGSR