SOXS_SALTY
ID SOXS_SALTY Reviewed; 107 AA.
AC Q56143;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Regulatory protein SoxS;
GN Name=soxS; OrderedLocusNames=STM4265;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RA Martins E.A.L., Demple B.;
RL Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Transcriptional activator of the superoxide response regulon
CC of E.coli that includes at least 10 genes such as sodA, nfo, zwf and
CC micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the
CC subsequent binding of RNA polymerase to the micF and the nfo promoters
CC (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
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DR EMBL; U61147; AAB03868.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL23089.1; -; Genomic_DNA.
DR RefSeq; NP_463130.1; NC_003197.2.
DR RefSeq; WP_000019483.1; NC_003197.2.
DR AlphaFoldDB; Q56143; -.
DR SMR; Q56143; -.
DR STRING; 99287.STM4265; -.
DR PaxDb; Q56143; -.
DR EnsemblBacteria; AAL23089; AAL23089; STM4265.
DR GeneID; 1255791; -.
DR KEGG; stm:STM4265; -.
DR PATRIC; fig|99287.12.peg.4486; -.
DR HOGENOM; CLU_000445_81_14_6; -.
DR OMA; FTMAWTR; -.
DR PhylomeDB; Q56143; -.
DR BioCyc; SENT99287:STM4265-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR Pfam; PF12833; HTH_18; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; SSF46689; 2.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 3: Inferred from homology;
KW Activator; Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..107
FT /note="Regulatory protein SoxS"
FT /id="PRO_0000194586"
FT DOMAIN 8..106
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 25..46
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 73..96
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ SEQUENCE 107 AA; 12970 MW; D6EB766056356662 CRC64;
MSHQQIIQTL IEWIDEHIDQ PLNIDVVAKK SGYSKWYLQR MFRTVTHQTL GEYIRQRRLL
LAAVELRTTE RPIFDIAMDL GYVSQQTFSR VFRREFDRTP SDYRHRL
