SP0M_BACSU
ID SP0M_BACSU Reviewed; 258 AA.
AC P71088; O87735; Q796Y7;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Sporulation-control protein spo0M;
DE AltName: Full=Stage 0 sporulation protein M;
GN Name=spo0M; Synonyms=ygaI; OrderedLocusNames=BSU08760;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 9-38 AND 188-209,
RP INDUCTION, AND FUNCTION.
RC STRAIN=168;
RX PubMed=9795118; DOI=10.1016/s0378-1119(98)00378-3;
RA Han W.-D., Kawamoto S., Hosoya Y., Fujita M., Sadaie Y., Suzuki K.,
RA Ohashi Y., Kawamura F., Ochi K.;
RT "A novel sporulation-control gene (spo0M) of Bacillus subtilis with a
RT sigmaH-regulated promoter.";
RL Gene 217:31-40(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9202460; DOI=10.1099/00221287-143-6-1855;
RA Cummings N.J., Connerton I.F.;
RT "The Bacillus subtilis 168 chromosome from sspE to katA.";
RL Microbiology 143:1855-1859(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP SEQUENCE REVISION TO 169; 198; 242 AND 257.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
CC -!- FUNCTION: Controls the expression of spo0A and is required to pass the
CC morphological stage 0 of sporulation. {ECO:0000269|PubMed:9795118}.
CC -!- INDUCTION: Expression controlled by a sigma-H-regulated promoter which
CC needs the sigma-H factor for the binding of the RNA polymerase and
CC subsequent transcription. {ECO:0000269|PubMed:9795118}.
CC -!- SIMILARITY: Belongs to the spo0M family. {ECO:0000305}.
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DR EMBL; D89936; BAA32616.1; -; Genomic_DNA.
DR EMBL; Z82044; CAB04803.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12704.2; -; Genomic_DNA.
DR PIR; D69816; D69816.
DR RefSeq; NP_388756.2; NC_000964.3.
DR RefSeq; WP_003233481.1; NZ_JNCM01000035.1.
DR PDB; 5CL2; X-ray; 2.30 A; A/B=11-258.
DR PDBsum; 5CL2; -.
DR AlphaFoldDB; P71088; -.
DR SMR; P71088; -.
DR IntAct; P71088; 1.
DR MINT; P71088; -.
DR STRING; 224308.BSU08760; -.
DR jPOST; P71088; -.
DR PaxDb; P71088; -.
DR EnsemblBacteria; CAB12704; CAB12704; BSU_08760.
DR GeneID; 939725; -.
DR KEGG; bsu:BSU08760; -.
DR PATRIC; fig|224308.179.peg.945; -.
DR eggNOG; COG4326; Bacteria.
DR InParanoid; P71088; -.
DR OMA; CHVWVET; -.
DR PhylomeDB; P71088; -.
DR BioCyc; BSUB:BSU08760-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.640; -; 1.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR009776; Spore_0_M.
DR PANTHER; PTHR40053; PTHR40053; 1.
DR Pfam; PF07070; Spo0M; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Reference proteome; Sporulation.
FT CHAIN 1..258
FT /note="Sporulation-control protein spo0M"
FT /id="PRO_0000359937"
FT CONFLICT 169
FT /note="L -> F (in Ref. 2; CAB04803)"
FT /evidence="ECO:0000305"
FT CONFLICT 198
FT /note="D -> G (in Ref. 2; CAB04803)"
FT /evidence="ECO:0000305"
FT CONFLICT 242
FT /note="T -> A (in Ref. 2; CAB04803)"
FT /evidence="ECO:0000305"
FT CONFLICT 257
FT /note="A -> V (in Ref. 2; CAB04803)"
FT /evidence="ECO:0000305"
FT STRAND 17..23
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 25..27
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 32..40
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 46..63
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 66..80
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 83..85
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 90..98
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 112..123
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 126..134
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 138..149
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 152..161
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 163..165
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 168..179
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 182..187
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 191..197
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 199..208
FT /evidence="ECO:0007829|PDB:5CL2"
FT TURN 210..214
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 220..222
FT /evidence="ECO:0007829|PDB:5CL2"
FT TURN 223..225
FT /evidence="ECO:0007829|PDB:5CL2"
FT STRAND 230..235
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 236..240
FT /evidence="ECO:0007829|PDB:5CL2"
FT HELIX 242..254
FT /evidence="ECO:0007829|PDB:5CL2"
FT TURN 255..257
FT /evidence="ECO:0007829|PDB:5CL2"
SQ SEQUENCE 258 AA; 29733 MW; 3FA37879510FE0B8 CRC64;
MSFFKKLAAS AGIGAAKVDT ILEKDAYFPG EEVQGTVHVK GGKIAQDIRY IDLQLSTRYV
IVKDDEEHRK YATIHSFRVT GSFTIQPGEE HQFPFTFTLP LDTPITVGKV EVAVVTDLDI
QGGIDKSDHD RIFVEAHPWI ENVLEAIENL GFRLNEADCE QAPYFQRRLP FVQEFEFVPT
SGYYRQMLDE LELIFLLDED GLEIIFEVDR RARGLRGWLE EMYNDGEQLV RVRFSQSELE
DTEELEEVLE EILDQYAE
