ID   SP110_ASHGO             Reviewed;         852 AA.
AC   Q756L3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Spindle pole body component 110;
DE   AltName: Full=Spindle pole body spacer protein SPC110;
GN   Name=SPC110; OrderedLocusNames=AER241W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the spindle pole body (SPB) required for the
CC       proper execution of spindle pole body (SPB) duplication. Potential role
CC       in cross-linking filaments or anchoring other molecules. It is
CC       essential for growth (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, spindle pole body {ECO:0000250}.
CC       Note=Tightly associated with the nucleus. It is present in a granular
CC       pattern that excludes the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPC110 family. {ECO:0000305}.
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DR   EMBL; AE016818; AAS52922.1; -; Genomic_DNA.
DR   RefSeq; NP_985098.1; NM_210452.1.
DR   AlphaFoldDB; Q756L3; -.
DR   SMR; Q756L3; -.
DR   STRING; 33169.AAS52922; -.
DR   PRIDE; Q756L3; -.
DR   EnsemblFungi; AAS52922; AAS52922; AGOS_AER241W.
DR   GeneID; 4621308; -.
DR   KEGG; ago:AGOS_AER241W; -.
DR   eggNOG; ENOG502QUTQ; Eukaryota.
DR   HOGENOM; CLU_329279_0_0_1; -.
DR   InParanoid; Q756L3; -.
DR   OMA; EISMYQE; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0000793; C:condensed chromosome; IBA:GO_Central.
DR   GO; GO:0000796; C:condensin complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IBA:GO_Central.
DR   InterPro; IPR041112; Nuf2_DHR10-like.
DR   InterPro; IPR040593; Spc110_C.
DR   Pfam; PF18595; DHR10; 1.
DR   Pfam; PF18520; Spc110_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..852
FT                   /note="Spindle pole body component 110"
FT                   /id="PRO_0000409198"
FT   COILED          158..711
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   852 AA;  101308 MW;  413A56FD5FAADE23 CRC64;
     MFASLDTPAV HQRKKYEFTP IGHIKEKENM IAQELRQNKR PPLEDEEDAA IEGNYMKRTR
     VGDDTMNSQQ LFNETSFDDT LPEQTLQGIS AIKKNLAPEL LSNDNKEKAE LASNPLKEQQ
     HALQKLNMEN YSLRVKCNSL LKFLNNVTDD GKLKQGLEML DELQEWKTKH HELIQRFKEL
     QLRYDELEQR EPEPLKVAEP ADHSHCEKLR AELETSLKET RSQLDEVQAT VSTLEKRLVE
     VKKDYSEKEH QYKMSLDIAK SENNRLTSSL SSREDALNEA QEKINRLMVQ LEEFDHTSGS
     LLELEKKIDD KNQGIRNLET RLQELNFHRQ DLERQLLTAN ETIEALKKEH EEYREQNELK
     LTSLHKNTSG EDRLRKQLRD LAEDKEGLQK LRQTLEERNK ELDERVEALE SQVAAIEEDR
     QKIIGEQQQV VRNLKLEHQK RAQNLKREIE ELRELNQQLE ETNRSYKKRF EHFSRNSPAR
     KATQEELTAK DREIGALKRT IRDIEESVLR TTRELETAKI QHRREKSMLE ARLDQAASEE
     PFERSRLEKE ISMLKLEIRS IQDTKERELS LWESKYESLK NTYEKLLQQD KHSNLNEILE
     DRREELKSLM KKYNDLTTEN LELTRELNKQ KSHKEAYKED LRKVQARLDF ITKEFVKLKE
     SAPEPKDSSD ELNSKWMEKY QNMKIKLLNE LKVLQDENIQ LERRLLDRSQ QQSHNLAETP
     TQSRDSSLQD KVDYYRLKYH DEVRKNNDLR VINEYLNRVL KASSQHLKLD ILKLENEISP
     LNSSTTYIND YDYSYAPSYY SRRGRPLKFK TVAIFVLSCI RMYQATLRRR WDQQRINYLQ
     RKIAYGEDRI TW