ID   SP110_CANGA             Reviewed;         872 AA.
AC   Q6FY25;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Spindle pole body component 110;
DE   AltName: Full=Spindle pole body spacer protein SPC110;
GN   Name=SPC110; OrderedLocusNames=CAGL0A02596g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the spindle pole body (SPB) required for the
CC       proper execution of spindle pole body (SPB) duplication. Potential role
CC       in cross-linking filaments or anchoring other molecules. It is
CC       essential for growth (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, spindle pole body {ECO:0000250}.
CC       Note=Tightly associated with the nucleus. It is present in a granular
CC       pattern that excludes the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPC110 family. {ECO:0000305}.
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DR   EMBL; CR380947; CAG57770.1; -; Genomic_DNA.
DR   RefSeq; XP_444877.1; XM_444877.1.
DR   AlphaFoldDB; Q6FY25; -.
DR   SMR; Q6FY25; -.
DR   STRING; 5478.XP_444877.1; -.
DR   PRIDE; Q6FY25; -.
DR   EnsemblFungi; CAG57770; CAG57770; CAGL0A02596g.
DR   GeneID; 2886370; -.
DR   KEGG; cgr:CAGL0A02596g; -.
DR   CGD; CAL0126697; CAGL0A02596g.
DR   VEuPathDB; FungiDB:CAGL0A02596g; -.
DR   eggNOG; ENOG502QUTQ; Eukaryota.
DR   HOGENOM; CLU_329279_0_0_1; -.
DR   InParanoid; Q6FY25; -.
DR   OMA; LMNANAK; -.
DR   Proteomes; UP000002428; Chromosome A.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR040593; Spc110_C.
DR   Pfam; PF18520; Spc110_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..872
FT                   /note="Spindle pole body component 110"
FT                   /id="PRO_0000409199"
FT   REGION          15..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          176..723
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        64..86
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   872 AA;  102928 MW;  98D9A9F38605495F CRC64;
     MSDIKNFEFT PIGYIKSKSG ENDAKETLMS PTGASVRSPG SVGHVRKARR RSINDTVNSS
     RVENDNDTFD ETLPELEMRK LPQYRRVPES RTSARNSGAA PQEEQNRNDY SDILSKTSNP
     IKDQEQKIKD LEHENTVLKV KNVSYRSLLA NYSGGSSQNN INLVEEVSIW KTKYLETNEK
     LLKVKQDFES YVQKMEQEKE VNTDQEKTKE PEVIPIDNPE YIKEREHILE ELERVTEDFK
     NLRDRYNDLE IKFLSIQNEL DEKKQEFESS TARLNEEIHT LKSTIDDKDA TISEFKRKLG
     NAEDQLASID DQNGNQNQKL LHDLKEREDA IDGLKEDIIE KENAIVHYKE EIQDKQNQLK
     ESESKYAEVQ KEFEDFKREL KKQTFEFEDG KKSTSRQLQE LSVEKIQLEK QVCNLRGQIE
     KLEQQHRLTQ SENDGLRTKL KHIESDLKNE KSRTEVKIKD LTSDLEDARK NLGEANNTIK
     ELHHEIIKNA TKSKDQLSEE VVEKDKEIDQ LKHRVQRLDE ELRTSQAELD KATKNREVDH
     ELEIRRLQNK HEIEQESLKR ELAHMTDEKE RLVDLHRLDI ETWERQIEAL RKENENLISR
     EHKESNNIEI TLQDKNIQIR RLEADIVQLN EERNDILNKL RSLEQAKDRY KSEMKDALET
     ISRLRVDLEN NKSLKDSKDS LIERKYEKLK DEFKLMKKGY LDEMIKLQSR NRELNSDLQK
     RMDPSISTSA NTTLADKLDY YKLKYNDEVR HNNDLRVINE YLNRVLRASA QDIRLNLLKV
     ENDLNIDIHK ENVPLSAPLS SSGGRPYSSS YTREFDKYDY RYRQKGKRFK TVALAVLAVI
     RMYRAAKKHN WNEQRIRYLQ RKIIAKEDRI TW