ID   SP110_ZYGRC             Reviewed;         835 AA.
AC   C5DY19;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Spindle pole body component 110;
DE   AltName: Full=Spindle pole body spacer protein SPC110;
GN   Name=SPC110; OrderedLocusNames=ZYRO0F09570g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Component of the spindle pole body (SPB) required for the
CC       proper execution of spindle pole body (SPB) duplication. Potential role
CC       in cross-linking filaments or anchoring other molecules. It is
CC       essential for growth (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, spindle pole body {ECO:0000250}.
CC       Note=Tightly associated with the nucleus. It is present in a granular
CC       pattern that excludes the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPC110 family. {ECO:0000305}.
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DR   EMBL; CU928178; CAR28680.1; -; Genomic_DNA.
DR   RefSeq; XP_002497613.1; XM_002497568.1.
DR   AlphaFoldDB; C5DY19; -.
DR   SMR; C5DY19; -.
DR   STRING; 559307.C5DY19; -.
DR   EnsemblFungi; CAR28680; CAR28680; ZYRO0F09570g.
DR   GeneID; 8205377; -.
DR   KEGG; zro:ZYRO0F09570g; -.
DR   HOGENOM; CLU_329279_0_0_1; -.
DR   InParanoid; C5DY19; -.
DR   Proteomes; UP000008536; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR040593; Spc110_C.
DR   Pfam; PF18520; Spc110_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..835
FT                   /note="Spindle pole body component 110"
FT                   /id="PRO_0000409206"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          73..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          685..706
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          182..690
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        25..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        690..706
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   835 AA;  97814 MW;  045CA73DD480C2CD CRC64;
     MADAPDHSLN GRRHLEFTPI GYSRQNPLKR LSRSPIQTVA EDDNNGNGMS EEGPFKKQRR
     ADLDDTIASH RMFNDSSQFD DTLPQLNGQS ADNDNDNAHD SGKETDDVVK NLMGNLKENA
     PASNPLKEQQ EQLHKLNTDN YNLRLKCNSL LKFLHNVTDQ GELTKSLGLL DEIHEWKQKH
     YTLNQQYLEL KAKLIQVEAN AAENKQEPVT EVDHTACQRE LSYVQNQLEK TTLQLNTYRD
     EVAHLEDKTI RIQEDQRAKE EQHQLEIQML RSDVNNLNVS LVNKESELEE DRAKIQRLMN
     QLHEFDHKGS QSLLDLERQL EMKRDSISSL EKEVRALTHD RVHLETRIKD REIENAKIQS
     ELERLRDNVK NNNSSNFEIG ELKHAKASLD DKVRNLTEER HNLNQRISAL RKECDEWKSK
     YQRNESLDSN HRKAFDSLRQ ELQTTKTQLE ETRKTAQQLQ TQVIENTTKN SERTSQRIKD
     KETQIQKLES ELQFCKQQLK DGSRRLQAEE ERCRETFESE LQNLEMKNGF ERTKLEREIT
     LLKEERVALI ETHDRELELW KSKCDALNKE NDILVRQEIG DLDGVKRKLS QQLDKLQEKL
     TTAEGERGDL AEKLIKLQHS KDSYKDELKR VSSKLEYLSK EYLKSKQSAI NDDEQKTKYN
     TMKQRLLVEL KSLQDENLSL ERKLLEQRGS SSRSQESSSR SSSTTQDRLD YYKLKYNNEV
     KHNNDLRIMN DYLNRVLRAS SQHLKLDLLK LESEISQPAV PSSRTYKTVL DDDRYRPRFR
     SGLISPGHIP TFKAVALLVL ACVRMKQTAV RCRWDEHRIR YLRNKMAIDD DRITW