ID   SP13B_XENLA             Reviewed;        1041 AA.
AC   Q5M7C3;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Histone deacetylase complex subunit SAP130-B;
DE   AltName: Full=130 kDa Sin3-associated polypeptide B;
DE   AltName: Full=Sin3-associated polypeptide p130 B;
GN   Name=sap130-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a transcriptional repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SAP130 family. {ECO:0000305}.
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DR   EMBL; BC088715; AAH88715.1; -; mRNA.
DR   RefSeq; NP_001088898.1; NM_001095429.1.
DR   AlphaFoldDB; Q5M7C3; -.
DR   SMR; Q5M7C3; -.
DR   PRIDE; Q5M7C3; -.
DR   DNASU; 496245; -.
DR   GeneID; 496245; -.
DR   KEGG; xla:496245; -.
DR   CTD; 496245; -.
DR   Xenbase; XB-GENE-6252221; sap130.L.
DR   OMA; IHQPIQA; -.
DR   OrthoDB; 242848at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 496245; Expressed in testis and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR024137; His_deAcase_cplx_SAP130.
DR   InterPro; IPR031963; SAP130_C.
DR   PANTHER; PTHR13497; PTHR13497; 1.
DR   Pfam; PF16014; SAP130_C; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..1041
FT                   /note="Histone deacetylase complex subunit SAP130-B"
FT                   /id="PRO_0000283740"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          111..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          572..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..769
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          806..852
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..28
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..640
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1041 AA;  109991 MW;  22F728557A5D5689 CRC64;
     MSSQQFPRQA VSMPPPQVSN SGASVGQNVQ GDEVAREIDV QSRDPLGAST VLPSRDDKQE
     PVVVRPYPQV QMLTSHHPLQ PAPSLTMTAQ PAHLTSAVPL SFSENILKTP KSTMPSRPIA
     PAPPSALSAV PKVSGQGTVT MESGLPQTSA IPVATISGQQ GHPNSLHHIM AATNVQMSII
     RSGAPGPPLH IGASHLPRGA AAAAVMSSSK VTTMLRPASA QIPSAAASQS ATQHIIHPPI
     QSRPPVTTTS VSPAVVATVS ATRAQSPVIT TTPAHAAEPV LRPTLAFQQH PPPAAISIQR
     SAQARDAATT RITLPTHPAL GGQKPQLHAM TQKTLFGTGN PVAAATVAPI LATNTLPSVT
     TSGSAPHTQV STSTIVTMTM PTHSSHATAG TASNIPVAKV VPQQITHTSP RIQSEYGTER
     GNLIPIPGHR ASPNPMTMEA RSENRQPVPV QLQYFLPTYP PSAYPLTAHT YTPITSSVST
     IRQYPVSAQA PNSAITAQSV ASTVHLNPMQ LINMDTSHTR HIQGIQPAPV SAQGIQPSPF
     SAQGIQATPI STQGIHPTPI NTQAIHPATS ITNQGVQTSS VSSQQASSEP KSSVVLAEGA
     TIIANPINSS FSATPAGTTV MQSHSQSPGI GSSPAQGSSP RPSILRKKPA TEGLSVRKSL
     IPPHPGDAVS PRHDSALRST SASPRPAGAK PKADLHVSVA PGVTGDPGAA DQPSAAASLP
     SSHHPTAAVP SPPSQPVSGP MPSSIHITPA TIPALSAPPP LLSNAPSGAV MPEDKMKEEA
     EPMDILRPVS AVPPLPPNSI SSPLTVLANN ISGPAGELPP GASPRKKPRK QQHVISTEEG
     DMMETNSTDE ERCHAVKPFT SRPEKRKSPP KEYIDEEGVR YVPVRPRPPI TLLRHYRNPW
     KAAYHHFQRY TDVRVKEEKK LTLQDVANQK GITCRVQGWK THLCAAQLLQ LIKLEQDVFE
     RLTVLQEGLV PKKKTATDDD LHRINELIQG NMQRCKLVMD QITESRDCML KVLDHKDRVL
     KLLNKSGASR RLSKVKPKDK M