ID   SP17_NOTEU              Reviewed;         153 AA.
AC   O62770;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Sperm surface protein Sp17;
DE   AltName: Full=Sperm autoantigenic protein 17;
GN   Name=SPA17; Synonyms=SP17;
OS   Notamacropus eugenii (Tammar wallaby) (Macropus eugenii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Macropodidae; Notamacropus.
OX   NCBI_TaxID=9315;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RA   Wen Y., O'Rand M.G.;
RL   Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sperm surface zona pellucida binding protein. Helps to bind
CC       spermatozoa to the zona pellucida with high affinity. Might function in
CC       binding zona pellucida and carbohydrates (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. May interact with ROPN1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Peripheral membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Testis- and sperm-specific.
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DR   EMBL; AF054289; AAC08024.1; -; mRNA.
DR   AlphaFoldDB; O62770; -.
DR   SMR; O62770; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
DR   InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR012105; Sp17.
DR   Pfam; PF00612; IQ; 1.
DR   Pfam; PF02197; RIIa; 1.
DR   PIRSF; PIRSF016533; Sp17; 1.
DR   SMART; SM00015; IQ; 1.
DR   SMART; SM00394; RIIa; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   2: Evidence at transcript level;
KW   Membrane.
FT   CHAIN           1..153
FT                   /note="Sperm surface protein Sp17"
FT                   /id="PRO_0000181341"
FT   DOMAIN          122..151
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          74..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   153 AA;  17327 MW;  AD3A7C6B4D4E1E65 CRC64;
     MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFENLLEKR EKTNFDPAEW
     GAKIDDRFYN NHAFKVPSGA TESKEAPPEK SEPEKETPQE VVKEQETQVS FVEEVSTDDE
     EAAAAAVKIQ AAFRGHKARK EVKIMKESSI EEQ