ID   SP17_PAPHA              Reviewed;         163 AA.
AC   Q95230;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Sperm surface protein Sp17;
DE   AltName: Full=Sperm autoantigenic protein 17;
GN   Name=SPA17; Synonyms=SP17;
OS   Papio hamadryas (Hamadryas baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=9110316;
RX   DOI=10.1002/(sici)1098-2795(199705)47:1<66::aid-mrd9>3.0.co;2-o;
RA   Adoyo P.A., Lea I.A., Richardson R.T., Widgren E.E., O'Rand M.G.;
RT   "Sequence and characterization of the sperm protein Sp17 from the baboon.";
RL   Mol. Reprod. Dev. 47:66-71(1997).
CC   -!- FUNCTION: Sperm surface zona pellucida binding protein. Helps to bind
CC       spermatozoa to the zona pellucida with high affinity. Might function in
CC       binding zona pellucida and carbohydrates (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. May interact with ROPN1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Peripheral membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Testis- and sperm-specific.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U75209; AAB38534.1; -; mRNA.
DR   AlphaFoldDB; Q95230; -.
DR   SMR; Q95230; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
DR   InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR012105; Sp17.
DR   Pfam; PF00612; IQ; 1.
DR   Pfam; PF02197; RIIa; 1.
DR   PIRSF; PIRSF016533; Sp17; 1.
DR   SMART; SM00015; IQ; 1.
DR   SMART; SM00394; RIIa; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   2: Evidence at transcript level;
KW   Membrane.
FT   CHAIN           1..163
FT                   /note="Sperm surface protein Sp17"
FT                   /id="PRO_0000181345"
FT   DOMAIN          114..143
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          57..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   163 AA;  18755 MW;  A890B59B3F6469BD CRC64;
     MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR EKTNFDPAEW
     GSKVEDRFYN NHAFEEQEPP EKSDPKQEES QVSGKEEETS VTILDSSEED KEKEEVAAVK
     IQAAFRGHVA REEVKKMKTD SLQNEEKEEN SEDTGFTSRT HEK