ID   SP20H_CHICK             Reviewed;         687 AA.
AC   Q5ZM71;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Transcription factor SPT20 homolog;
GN   Name=SUPT20H; Synonyms=FAM48A; ORFNames=RCJMB04_2p6;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or
CC       MAPK14) activation during gastrulation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPT20 family. {ECO:0000305}.
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DR   EMBL; AJ719513; CAG31172.1; -; mRNA.
DR   RefSeq; NP_001006275.1; NM_001006275.1.
DR   AlphaFoldDB; Q5ZM71; -.
DR   SMR; Q5ZM71; -.
DR   STRING; 9031.ENSGALP00000035685; -.
DR   PaxDb; Q5ZM71; -.
DR   GeneID; 418896; -.
DR   KEGG; gga:418896; -.
DR   CTD; 55578; -.
DR   VEuPathDB; HostDB:geneid_418896; -.
DR   eggNOG; ENOG502QS30; Eukaryota.
DR   InParanoid; Q5ZM71; -.
DR   OrthoDB; 369747at2759; -.
DR   PhylomeDB; Q5ZM71; -.
DR   PRO; PR:Q5ZM71; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR   GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR021950; Spt20.
DR   PANTHER; PTHR13526; PTHR13526; 3.
DR   Pfam; PF12090; Spt20; 2.
PE   2: Evidence at transcript level;
KW   Developmental protein; Gastrulation; Reference proteome.
FT   CHAIN           1..687
FT                   /note="Transcription factor SPT20 homolog"
FT                   /id="PRO_0000187043"
FT   REGION          423..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          666..687
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..481
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        482..497
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        666..681
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   687 AA;  74890 MW;  854A6B5118FA5367 CRC64;
     MQQALEQALD RAEYIIESAR QRPPKRKYLS SGRKSVFQKL YDLYIEECEK EPEIKKLRRN
     VNLLEKLVMQ ETLSCLVVNL YPGNEGYSLM LRGKNGSDSE TIRLPYEEGE LLEYLDAEEL
     PPILVDLLEK SQVNIFHCGC VIAEIRDYRQ SGNMKSPTYQ SKHILLRPTM QALICDVHSI
     TSDNHKWTQE DKLLLESQLI LATAEPLCLD PSIAVTCTTN RLLYNKQKMN TRPMKRCFKR
     YSKSSLNRQQ EVAHYSTPPQ LRLVDYLQKR KGKKGAQQYD LKISKAGNCV DMWKQNPCYL
     TAPSEVDVEK YAKVESSIKP DDSQPTVWPA HEVKDDYVFE CEVGNQLQKT KLTIFQSLGN
     PLYYGKIQTL KGDDESDSLL VPPQFLIGSK TDAERVVNQY HELVKSEAKC PVKMFHNSGG
     SINLSHLSPG KEMEPESISG SVQSSVLGKG VKHRPPPIKL PSSSGSSSSG NIFSPQQSSG
     HLKSPTPPPP PPTSKPPGLS RKQSMDLNQV SMLSPAAMSP ASSSQRTTST QVMANPAGLN
     FINVVGSVCG AQTLMSGSNP MLGCNTGAIA PAGINLSGIL PSGGLVPSAL PATMQSASQA
     GSPFGLKNAS NLRPLNLLQG SDQGPSNQDQ ALSAQQAAVI NLTGVGNFMQ PQATAVAILA
     ASNGYGSSSS TSSSSATSAA FRQPLKK