ID   SP21_STIAD              Reviewed;         169 AA.
AC   Q06823; Q08V45;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Spore protein SP21;
GN   Name=hspA; OrderedLocusNames=STAUR_4298; ORFNames=STIAU_6511;
OS   Stigmatella aurantiaca (strain DW4/3-1).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Archangiaceae; Stigmatella.
OX   NCBI_TaxID=378806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DW4/3-1;
RX   PubMed=8226695; DOI=10.1128/jb.175.22.7479-7482.1993;
RA   Heidelbach M., Skladny H., Schairer H.U.;
RT   "Heat shock and development induce synthesis of a low-molecular-weight
RT   stress-responsive protein in the myxobacterium Stigmatella aurantiaca.";
RL   J. Bacteriol. 175:7479-7482(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DW4/3-1;
RA   Nierman W.C.;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DW4/3-1;
RX   PubMed=21037205; DOI=10.1093/molbev/msq292;
RA   Huntley S., Hamann N., Wegener-Feldbruegge S., Treuner-Lange A., Kube M.,
RA   Reinhardt R., Klages S., Mueller R., Ronning C.M., Nierman W.C.,
RA   Sogaard-Andersen L.;
RT   "Comparative genomic analysis of fruiting body formation in Myxococcales.";
RL   Mol. Biol. Evol. 28:1083-1097(2011).
RN   [4]
RP   PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=DW4;
RX   PubMed=8423161; DOI=10.1128/jb.175.3.905-908.1993;
RA   Heidelbach M., Skladny H., Schairer H.U.;
RT   "Purification and characterization of SP21, a development-specific protein
RT   of the myxobacterium Stigmatella aurantiaca.";
RL   J. Bacteriol. 175:905-908(1993).
CC   -!- FUNCTION: May stabilize cellular components during stress and spore
CC       formation.
CC   -!- DEVELOPMENTAL STAGE: During fruiting and upon induced sporulation.
CC   -!- INDUCTION: By stress, such as heat shock and oxygen limitation.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; M94510; AAA16136.1; -; Unassigned_DNA.
DR   EMBL; AAMD01000121; EAU64354.1; -; Genomic_DNA.
DR   EMBL; CP002271; ADO72078.1; -; Genomic_DNA.
DR   PIR; A49942; A49942.
DR   RefSeq; WP_002616692.1; NZ_AAMD01000121.1.
DR   AlphaFoldDB; Q06823; -.
DR   SMR; Q06823; -.
DR   STRING; 378806.STAUR_4298; -.
DR   EnsemblBacteria; ADO72078; ADO72078; STAUR_4298.
DR   EnsemblBacteria; EAU64354; EAU64354; STIAU_6511.
DR   KEGG; sur:STAUR_4298; -.
DR   eggNOG; COG0071; Bacteria.
DR   HOGENOM; CLU_046737_12_2_7; -.
DR   OMA; FEITAEL; -.
DR   OrthoDB; 1523369at2; -.
DR   Proteomes; UP000001351; Chromosome.
DR   Proteomes; UP000032702; Unassembled WGS sequence.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Sporulation;
KW   Stress response.
FT   CHAIN           1..169
FT                   /note="Spore protein SP21"
FT                   /id="PRO_0000126059"
FT   DOMAIN          47..159
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        111
FT                   /note="S -> T (in Ref. 1; AAA16136)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        169
FT                   /note="A -> AYPAPAEPGLAAPLGWPGFS (in Ref. 1; AAA16136)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   169 AA;  19359 MW;  0D1AAB05BFE4FF6A CRC64;
     MADLSVRRGT GSTPQRTREW DPFQQMQELM NWDPFELANH PWFANRQGPP AFVPAFEVRE
     TKEAYIFKAD LPGVDEKDIE VTLTGDRVSV SGKREREKRE ESERFYAYER SFGSFSRAFT
     LPEGVDGDNV RADLKNGVLT LTLPKRPEVQ PKRIQVASSG TEQKEHIKA