ID   SP2AA_PRIMG             Reviewed;         116 AA.
AC   P35147;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Anti-sigma F factor antagonist;
DE   AltName: Full=Stage II sporulation protein AA;
GN   Name=spoIIAA;
OS   Priestia megaterium (Bacillus megaterium).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Priestia.
OX   NCBI_TaxID=1404;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1391049; DOI=10.1016/0300-9084(92)90142-2;
RA   Tao Y.P., Hudspeth D.S.S., Vary P.S.;
RT   "Cloning and sequencing of the Bacillus megaterium spoIIA operon.";
RL   Biochimie 74:695-704(1992).
CC   -!- FUNCTION: In the phosphorylated form it could act as an anti-anti-sigma
CC       factor that counteracts SpoIIAB and thus releases sigma f from
CC       inhibition. {ECO:0000250}.
CC   -!- PTM: Phosphorylated by SpoIIAB on a serine residue.
CC   -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC       {ECO:0000305}.
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DR   EMBL; X63757; CAA45286.1; -; Genomic_DNA.
DR   PIR; A48402; A48402.
DR   AlphaFoldDB; P35147; -.
DR   SMR; P35147; -.
DR   GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR   GO; GO:0045152; F:antisigma factor binding; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR003658; Anti-sigma_ant.
DR   InterPro; IPR014237; Anti-sigma_F_ant.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   Pfam; PF01740; STAS; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   TIGRFAMs; TIGR00377; ant_ant_sig; 1.
DR   TIGRFAMs; TIGR02886; spore_II_AA; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Sporulation.
FT   CHAIN           1..116
FT                   /note="Anti-sigma F factor antagonist"
FT                   /id="PRO_0000194201"
FT   DOMAIN          3..113
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   MOD_RES         58
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   116 AA;  12958 MW;  6447D53B126EEEF2 CRC64;
     MSLSIELEFK QDVLLVRLTG ELDHHTAEEL RSKITEAIEK ESISHLILNL QHLTFMDSSG
     LGVILGRYKQ VHNNGGEMVV CAISPAIERL FNMSGLFKII RFEPNEANAL QKLGVA