ID   SP2AA_WEICA             Reviewed;         116 AA.
AC   P70877;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 2.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Anti-sigma F factor antagonist;
DE   AltName: Full=Stage II sporulation protein AA;
GN   Name=spoIIAA;
OS   Weizmannia coagulans (Bacillus coagulans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Weizmannia.
OX   NCBI_TaxID=1398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 7050 / DSM 1 / JCM 2257 / CCUG 7417 / NBRC 12583 / NCIMB 9365 /
RC   NCTC 10334 / NRS 609;
RX   PubMed=8921882; DOI=10.1016/0378-1119(96)00306-x;
RA   Park S.G., Yudkin M.D.;
RT   "Nucleotide sequence of the Bacillus coagulans homologue of the spoIIA
RT   operon of Bacillus subtilis.";
RL   Gene 177:275-276(1996).
CC   -!- FUNCTION: In the phosphorylated form it could act as an anti-anti-sigma
CC       factor that counteracts SpoIIAB and thus releases sigma f from
CC       inhibition. {ECO:0000250}.
CC   -!- PTM: Phosphorylated by SpoIIAB on a serine residue. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC       {ECO:0000305}.
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DR   EMBL; Z54161; CAA90872.1; -; Genomic_DNA.
DR   PIR; JC5188; JC5188.
DR   RefSeq; WP_014098106.1; NZ_SMSP02000059.1.
DR   AlphaFoldDB; P70877; -.
DR   SMR; P70877; -.
DR   STRING; 1398.AB434_3357; -.
DR   GeneID; 29814587; -.
DR   GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR   GO; GO:0045152; F:antisigma factor binding; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR003658; Anti-sigma_ant.
DR   InterPro; IPR014237; Anti-sigma_F_ant.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   Pfam; PF01740; STAS; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   TIGRFAMs; TIGR00377; ant_ant_sig; 1.
DR   TIGRFAMs; TIGR02886; spore_II_AA; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Sporulation.
FT   CHAIN           1..116
FT                   /note="Anti-sigma F factor antagonist"
FT                   /id="PRO_0000194199"
FT   DOMAIN          3..113
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   MOD_RES         58
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   116 AA;  12972 MW;  FD7E890DB1C106F2 CRC64;
     MSLAIDLEVK KDVLCIRLQG ELDHHTAESL RASVTKAIEE NGIRHLVLNL EQLSFMDSSG
     LGVILGRYKQ IKQKNGEMIV CAISPAVKRL FELSGLFKII RLDESEQYAL HRLGVA