ID   SP3D_BACSU              Reviewed;          93 AA.
AC   P15281; P94579;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 144.
DE   RecName: Full=Stage III sporulation protein D;
DE   AltName: Full=14 kDa transcription factor;
GN   Name=spoIIID; OrderedLocusNames=BSU36420;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / PY79;
RX   PubMed=2514119; DOI=10.1101/gad.3.11.1735;
RA   Kunkel B., Kroos L., Poth H., Youngman P., Losick R.;
RT   "Temporal and spatial control of the mother-cell regulatory gene spoIIID of
RT   Bacillus subtilis.";
RL   Genes Dev. 3:1735-1744(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=2112673; DOI=10.1111/j.1365-2958.1990.tb00622.x;
RA   Stevens C.M., Errington J.;
RT   "Differential gene expression during sporulation in Bacillus subtilis:
RT   structure and regulation of the spoIIID gene.";
RL   Mol. Microbiol. 4:543-551(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353933; DOI=10.1099/00221287-143-10-3313;
RA   Presecan E., Moszer I., Boursier L., Cruz Ramos H., De La Fuente V.,
RA   Hullo M.-F., Lelong C., Schleich S., Sekowska A., Song B.H., Villani G.,
RA   Kunst F., Danchin A., Glaser P.;
RT   "The Bacillus subtilis genome from gerBC (311 degrees) to licR (334
RT   degrees).";
RL   Microbiology 143:3313-3328(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [5]
RP   PROTEIN SEQUENCE OF 1-34.
RX   PubMed=2492118; DOI=10.1126/science.2492118;
RA   Kroos L., Kunkel B., Losick R.;
RT   "Switch protein alters specificity of RNA polymerase containing a
RT   compartment-specific sigma factor.";
RL   Science 243:526-529(1989).
CC   -!- FUNCTION: This protein regulates the transcription of sigK, which
CC       encodes mother cell chamber RNA polymerase sigma-factor (sigma K).
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DR   EMBL; X15520; CAA33541.1; -; Genomic_DNA.
DR   EMBL; X52076; CAA36295.1; -; Genomic_DNA.
DR   EMBL; Z82987; CAB05384.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15659.1; -; Genomic_DNA.
DR   PIR; A33472; A33472.
DR   RefSeq; NP_391523.1; NC_000964.3.
DR   RefSeq; WP_003221804.1; NZ_JNCM01000034.1.
DR   PDB; 2L0K; NMR; -; A=1-93.
DR   PDBsum; 2L0K; -.
DR   AlphaFoldDB; P15281; -.
DR   SMR; P15281; -.
DR   STRING; 224308.BSU36420; -.
DR   PaxDb; P15281; -.
DR   PRIDE; P15281; -.
DR   EnsemblBacteria; CAB15659; CAB15659; BSU_36420.
DR   GeneID; 23411654; -.
DR   GeneID; 64305411; -.
DR   GeneID; 936917; -.
DR   KEGG; bsu:BSU36420; -.
DR   PATRIC; fig|224308.179.peg.3942; -.
DR   eggNOG; COG1609; Bacteria.
DR   OMA; VHKDMTE; -.
DR   PhylomeDB; P15281; -.
DR   BioCyc; BSUB:BSU36420-MON; -.
DR   PRO; PR:P15281; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR014208; Spore_III_D.
DR   InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR   Pfam; PF12116; SpoIIID; 1.
DR   TIGRFAMs; TIGR02844; spore_III_D; 1.
DR   PROSITE; PS00894; HTH_DEOR_1; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; DNA-binding; Reference proteome;
KW   Repressor; Sporulation; Transcription; Transcription regulation.
FT   CHAIN           1..93
FT                   /note="Stage III sporulation protein D"
FT                   /id="PRO_0000050269"
FT   DOMAIN          4..75
FT                   /note="HTH deoR-type"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   HELIX           5..19
FT                   /evidence="ECO:0007829|PDB:2L0K"
FT   HELIX           23..30
FT                   /evidence="ECO:0007829|PDB:2L0K"
FT   HELIX           34..41
FT                   /evidence="ECO:0007829|PDB:2L0K"
FT   HELIX           44..48
FT                   /evidence="ECO:0007829|PDB:2L0K"
FT   HELIX           50..65
FT                   /evidence="ECO:0007829|PDB:2L0K"
FT   HELIX           67..80
FT                   /evidence="ECO:0007829|PDB:2L0K"
SQ   SEQUENCE   93 AA;  10802 MW;  F1448B7805B964C3 CRC64;
     MHDYIKERTI KIGKYIVETK KTVRVIAKEF GVSKSTVHKD LTERLPEINP DLANEVKEIL
     DYHKSIRHLR GGEATKLKYK KDEILEGEPV QQS