SP5G_BACSU
ID SP5G_BACSU Reviewed; 97 AA.
AC P28015;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Putative septation protein SpoVG;
DE AltName: Full=Stage V sporulation protein G;
GN Name=spoVG; OrderedLocusNames=BSU00490;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=1373326; DOI=10.1016/0167-4781(92)90536-9;
RA Hudspeth D.S.S., Vary P.S.;
RT "spoVG sequence of Bacillus megaterium and Bacillus subtilis.";
RL Biochim. Biophys. Acta 1130:229-231(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP PROTEIN SEQUENCE OF 1-11.
RC STRAIN=168 / JH642;
RX PubMed=8755892; DOI=10.1128/jb.178.15.4611-4619.1996;
RA Graumann P., Schroeder K., Schmid R., Marahiel M.A.;
RT "Cold shock stress-induced proteins in Bacillus subtilis.";
RL J. Bacteriol. 178:4611-4619(1996).
RN [5]
RP FUNCTION IN SEPTATION.
RX PubMed=10348850; DOI=10.1128/jb.181.11.3392-3401.1999;
RA Matsuno K., Sonenshein A.L.;
RT "Role of SpoVG in asymmetric septation in Bacillus subtilis.";
RL J. Bacteriol. 181:3392-3401(1999).
CC -!- FUNCTION: Essential for sporulation. Interferes with or is a negative
CC regulator of the pathway leading to asymmetric septation.
CC {ECO:0000269|PubMed:10348850}.
CC -!- DEVELOPMENTAL STAGE: Specific to stage V sporulation.
CC -!- SIMILARITY: Belongs to the SpoVG family. {ECO:0000305}.
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DR EMBL; X62378; CAA44242.1; -; Genomic_DNA.
DR EMBL; D26185; BAA05284.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11825.1; -; Genomic_DNA.
DR PIR; S18902; S18902.
DR RefSeq; NP_387930.1; NC_000964.3.
DR RefSeq; WP_009966269.1; NZ_JNCM01000028.1.
DR PDB; 2IA9; X-ray; 3.00 A; A/B/C/D/E/F=1-97.
DR PDBsum; 2IA9; -.
DR AlphaFoldDB; P28015; -.
DR SMR; P28015; -.
DR IntAct; P28015; 1.
DR MINT; P28015; -.
DR STRING; 224308.BSU00490; -.
DR PaxDb; P28015; -.
DR PRIDE; P28015; -.
DR DNASU; 936959; -.
DR EnsemblBacteria; CAB11825; CAB11825; BSU_00490.
DR GeneID; 936959; -.
DR KEGG; bsu:BSU00490; -.
DR PATRIC; fig|224308.179.peg.49; -.
DR eggNOG; COG2088; Bacteria.
DR InParanoid; P28015; -.
DR OMA; KDVAHPI; -.
DR PhylomeDB; P28015; -.
DR BioCyc; BSUB:BSU00490-MON; -.
DR EvolutionaryTrace; P28015; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0030436; P:asexual sporulation; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1120.40; -; 1.
DR HAMAP; MF_00819; SpoVG; 1.
DR InterPro; IPR007170; SpoVG.
DR InterPro; IPR036751; SpoVG_sf.
DR PANTHER; PTHR38429; PTHR38429; 1.
DR Pfam; PF04026; SpoVG; 1.
DR SUPFAM; SSF160537; SSF160537; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell cycle; Cell division; Direct protein sequencing;
KW Reference proteome; Septation; Sporulation.
FT CHAIN 1..97
FT /note="Putative septation protein SpoVG"
FT /id="PRO_0000157188"
FT STRAND 3..10
FT /evidence="ECO:0007829|PDB:2IA9"
FT STRAND 13..25
FT /evidence="ECO:0007829|PDB:2IA9"
FT TURN 26..28
FT /evidence="ECO:0007829|PDB:2IA9"
FT STRAND 29..39
FT /evidence="ECO:0007829|PDB:2IA9"
FT STRAND 42..46
FT /evidence="ECO:0007829|PDB:2IA9"
FT STRAND 49..51
FT /evidence="ECO:0007829|PDB:2IA9"
FT STRAND 57..65
FT /evidence="ECO:0007829|PDB:2IA9"
FT HELIX 66..90
FT /evidence="ECO:0007829|PDB:2IA9"
SQ SEQUENCE 97 AA; 10893 MW; 3607EFC67EA83075 CRC64;
MEVTDVRLRR VNTDGRMRAI ASITLDHEFV VHDIRVIDGN NGLFVAMPSK RTPDGEFRDI
THPINSSTRG KIQDAVLNEY HRLGDTEALE FEEAGAS
