SP70_DICDI
ID SP70_DICDI Reviewed; 537 AA.
AC P15269; P08126; Q550W9; Q86AV8;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 2.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Spore coat protein SP70;
DE AltName: Full=Protein Beejin;
DE Flags: Precursor;
GN Name=cotB; ORFNames=DDB_G0276761;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2601718; DOI=10.1128/mcb.9.11.5215-5218.1989;
RA Fosnaugh K.L., Loomis W.F.;
RT "Spore coat genes SP60 and SP70 of Dictyostelium discoideum.";
RL Mol. Cell. Biol. 9:5215-5218(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [4]
RP PRELIMINARY NUCLEOTIDE SEQUENCE OF 72-170.
RX PubMed=3023394; DOI=10.1083/jcb.103.5.1999;
RA Gomer R.H., Datta S., Firtel R.A.;
RT "Cellular and subcellular distribution of a cAMP-regulated prestalk protein
RT and prespore protein in Dictyostelium discoideum: a study on the ontogeny
RT of prestalk and prespore cells.";
RL J. Cell Biol. 103:1999-2015(1986).
CC -!- PTM: Phosphorylated and fucosylated.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA33252.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; M26238; AAA33252.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AAFI02000019; EAL68882.1; -; Genomic_DNA.
DR PIR; B25439; B25439.
DR PIR; B33485; B33485.
DR RefSeq; XP_642813.1; XM_637721.1.
DR AlphaFoldDB; P15269; -.
DR STRING; 44689.DDB0185091; -.
DR PaxDb; P15269; -.
DR EnsemblProtists; EAL68882; EAL68882; DDB_G0276761.
DR GeneID; 8620676; -.
DR KEGG; ddi:DDB_G0276761; -.
DR dictyBase; DDB_G0276761; cotB.
DR eggNOG; ENOG502RD3M; Eukaryota.
DR HOGENOM; CLU_507566_0_0_1; -.
DR InParanoid; P15269; -.
DR OMA; CPIIPIC; -.
DR PhylomeDB; P15269; -.
DR PRO; PR:P15269; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0090665; C:glycoprotein complex; IDA:dictyBase.
DR GO; GO:0031160; C:spore wall; IDA:dictyBase.
DR GO; GO:0003677; F:DNA binding; IDA:dictyBase.
DR GO; GO:0031153; P:slug development involved in sorocarp development; IEP:dictyBase.
DR GO; GO:0042244; P:spore wall assembly; IMP:dictyBase.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
DR InterPro; IPR007643; Dict_spore_N.
DR InterPro; IPR003645; Fol_N.
DR Pfam; PF04562; Dicty_spore_N; 1.
DR SMART; SM00274; FOLN; 5.
PE 3: Inferred from homology;
KW Glycoprotein; Phosphoprotein; Reference proteome; Repeat; Signal;
KW Sporulation.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..537
FT /note="Spore coat protein SP70"
FT /id="PRO_0000032671"
FT DOMAIN 21..140
FT /note="DSCP-N"
FT DOMAIN 157..179
FT /note="Follistatin-like 1"
FT DOMAIN 250..272
FT /note="Follistatin-like 2"
FT DOMAIN 278..296
FT /note="Follistatin-like 3"
FT DOMAIN 358..380
FT /note="Follistatin-like 4"
FT DOMAIN 389..415
FT /note="Follistatin-like 5"
FT REGION 183..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 97
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 537 AA; 56584 MW; 0B809A54A7A60AA3 CRC64;
MRILKLAALS CLLFIAPSLS INCDGLSKDQ CEQNFPQCQI LTAKSCCGES KSYCAERDSN
DCLASKISCK KDPQGNIYEF WSSCTPSSGF TDFIPSNATC SSLNCNAQQM SCKYVQQACH
ETSCCPDIPQ CQIPATGGGP ATGSATGQGT SGGTPGSCDK VNCPNGYICT IVNQLAVCVS
PSSSSSSSSS TTGSHTTTGG STTGSHTTTG GSTTGSHTTT GGSTTGSHTT TGGSTTGSHT
TTGGSTTGPT CGNVNCPRGY HCEVRGSQAV CVADEFDSCA NVDCGSGYHC KNGECIRDKV
ECDACDQINC PKGHHCISQP KGGWIGSHKK RHWQLHPEHC GGRPNKIKVI CVPSPKGTCK
TVQCPKGYKC KLYADGPTCV KIEKPKCLTC KDMHCESNGL LCVLTPQKKT DEECCPIIPI
CINPSTIAAS TIATTTASTR HSTASTIASL VTGTTSGGGG MGSFGGRSDE ESSDPNAILG
LFEDDIFWGD NDEYFSDNYR YVDEEDIDED FNGNDEFEID VEGDFQEDDF EEEYAFY
