ID   SPAC_BACIU              Reviewed;         441 AA.
AC   P33115;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Subtilin biosynthesis protein SpaC;
GN   Name=spaC;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 6633 / PCI 219 / NRS 231;
RX   PubMed=1539969; DOI=10.1128/aem.58.1.132-142.1992;
RA   Klein C., Kaletta C., Schnell N., Entian K.-D.;
RT   "Analysis of genes involved in biosynthesis of the lantibiotic subtilin.";
RL   Appl. Environ. Microbiol. 58:132-142(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 6633 / PCI 219 / NRS 231;
RX   PubMed=1735728; DOI=10.1128/jb.174.4.1417-1422.1992;
RA   Chung Y.J., Steen M.T., Hansen J.N.;
RT   "The subtilin gene of Bacillus subtilis ATCC 6633 is encoded in an operon
RT   that contains a homolog of the hemolysin B transport protein.";
RL   J. Bacteriol. 174:1417-1422(1992).
CC   -!- FUNCTION: Could be implicated in the processing or the export process
CC       of the subtilin lantibiotic.
CC   -!- SIMILARITY: To S.epidermidis EpiC and L.lactis NisC. {ECO:0000305}.
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DR   EMBL; M86869; AAA22839.1; -; Genomic_DNA.
DR   EMBL; M83944; AAA22771.1; -; Genomic_DNA.
DR   EMBL; M99263; AAA22777.1; -; Genomic_DNA.
DR   EMBL; U09819; AAB91588.1; -; Genomic_DNA.
DR   PIR; C43935; C43935.
DR   AlphaFoldDB; P33115; -.
DR   SMR; P33115; -.
DR   CDD; cd04793; LanC; 1.
DR   InterPro; IPR033889; LanC.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR020452; Subtilin_biosynthesis_SpaC.
DR   Pfam; PF05147; LANC_like; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   PRINTS; PR01953; SPACPROTEIN.
DR   SMART; SM01260; LANC_like; 1.
PE   4: Predicted;
FT   CHAIN           1..441
FT                   /note="Subtilin biosynthesis protein SpaC"
FT                   /id="PRO_0000072092"
FT   CONFLICT        128
FT                   /note="D -> S (in Ref. 2; AAA22771/AAA22777)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        255
FT                   /note="A -> R (in Ref. 2; AAA22771/AAA22777)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        403
FT                   /note="E -> D (in Ref. 2; AAA22771/AAA22777)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   441 AA;  49310 MW;  6E7453BBF491D408 CRC64;
     MERGTVSRIE VEIVKEMARQ ISNYDKVLEI VNQKDNFRSI GEVPLIPWKS TALSHGIPGI
     CMLYGELHAH FPEEGWDDIG HQYLSILVNE IKEKGLHTPS MFSGAAGIGL AAICLSQRFT
     YYNGLISDIN EYLAETVPQL LTEFDQRQVC MSDYDVIEGV SGIANYLLLF QEDKAMGDLL
     IDILKYLVRL TEDIIVDGEK VPGWHIPSQH QFTDIEKKAY PYGNFNMGLA HGIPGPICVL
     SSALIQGIKV KGQEAAIEKM ANFLLEFSEK EQDSLFWKGI ISFEEYQYGS PPNAVNFSRD
     AWCYGRPGVC LALVKAGKAL QNTELINIGV QNLRYTISDI RGIFSPTICH GYSGIGQILL
     AVNLLTGQEY FKEELQEIKQ KIMSYYDKDY IFGFHNYESM EGEEAVPLQY VGLLDGAVGV
     GLGVLNMELG SKTDWTKALL I