ID   SPAK_SHISO              Reviewed;         133 AA.
AC   Q55296;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Surface presentation of antigens protein SpaK;
DE   AltName: Full=Class 1B type III secretion system chaperone spa15;
GN   Name=spaK; Synonyms=spa15;
OS   Shigella sonnei.
OG   Plasmid pINV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HW383;
RA   Arakawa E., Kato J., Ito K., Watanabe H.;
RT   "Comparison and high conservation of nucleotide sequences of spa-mxi
RT   regions between S.sonnei and S.flexneri -- identification of a new gene
RT   coding plausible membrane protein.";
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for surface presentation of invasion plasmid
CC       antigens. Chaperone specialized in the storage of effectors within the
CC       bacterial cytoplasm, maintaining them in a secretion-competent state,
CC       and allowing their immediate delivery to target cells upon contact of
CC       the bacterium with the host cells.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SpaK family. {ECO:0000305}.
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DR   EMBL; D50601; BAA09157.1; -; Genomic_DNA.
DR   RefSeq; WP_000065501.1; NZ_UIQD01000016.1.
DR   AlphaFoldDB; Q55296; -.
DR   SMR; Q55296; -.
DR   STRING; 216599.GCA_000283715_05239; -.
DR   OMA; TIMEGCQ; -.
DR   InterPro; IPR003065; Invas_SpaK.
DR   Pfam; PF03519; Invas_SpaK; 1.
DR   PRINTS; PR01305; SSPAKPROTEIN.
PE   3: Inferred from homology;
KW   Chaperone; Plasmid; Virulence.
FT   CHAIN           1..133
FT                   /note="Surface presentation of antigens protein SpaK"
FT                   /id="PRO_0000180967"
SQ   SEQUENCE   133 AA;  15188 MW;  EA8F173A85A002B1 CRC64;
     MSNINLVQLV RDSLFTIGCP PSIITDLDSH SAITISLDSM PAINIALVNE QVMLWANFDA
     PSDVKLQSSA YNILNLMLMN FSYSINELVE LHRSDEYLQL RVVIKDDYVH DGIVFAEILH
     EFYQRMEILN EVL