ID   SPAO_SHISO              Reviewed;         293 AA.
AC   P0A1L0; P35534; Q8VSG8;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Surface presentation of antigens protein SpaO;
DE   AltName: Full=Spa33 protein;
GN   Name=spaO; Synonyms=spa33;
OS   Shigella sonnei.
OG   Plasmid pINV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HW383;
RA   Arakawa E., Kato J., Ito K., Watanabe H.;
RT   "Comparison and high conservation of nucleotide sequences of spa-mxi
RT   regions between S.sonnei and S.flexneri -- identification of a new gene
RT   coding plausible membrane protein.";
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for surface presentation of invasion plasmid
CC       antigens. Could play a role in preserving the translocation competence
CC       of the Ipa antigens. Required for invasion and for secretion of the
CC       three Ipa proteins (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliN/MopA/SpaO family. {ECO:0000305}.
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DR   EMBL; D50601; BAA09161.1; -; Genomic_DNA.
DR   RefSeq; WP_000944309.1; NZ_WHSK01000261.1.
DR   AlphaFoldDB; P0A1L0; -.
DR   SMR; P0A1L0; -.
DR   STRING; 216599.GCA_000283715_05243; -.
DR   OMA; DWVIRID; -.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 2.30.330.10; -; 1.
DR   InterPro; IPR001543; FliN-like_C.
DR   InterPro; IPR036429; SpoA-like_sf.
DR   InterPro; IPR003283; T3SS_OMP_SpaO.
DR   Pfam; PF01052; FliMN_C; 1.
DR   PRINTS; PR01339; TYPE3OMOPROT.
DR   SUPFAM; SSF101801; SSF101801; 1.
PE   3: Inferred from homology;
KW   Plasmid; Virulence.
FT   CHAIN           1..293
FT                   /note="Surface presentation of antigens protein SpaO"
FT                   /id="PRO_0000184128"
SQ   SEQUENCE   293 AA;  33418 MW;  5AC0BCDD96223E77 CRC64;
     MLRIKHFDAN EKLQILYAKQ LCERFSIQTF KNKFTGSESL VTLTSVCGDW VIRIDTLSFL
     KKKYEVFSGF STQESLLHLS KCVFIESSSV FSIPELSDKI TFRITNEIQY ATTGSHLCCF
     SSSLGIIYFD KMPVLRNQVS LDLLHHLLEF CLGSSNVRLA TLKRIRTGDI IIVQKLYNLL
     LCNQVIIGDY IVNDNNEAKI NLSESNGESE HTEVSLALFN YDDINVKVDF ILLEKNMTIN
     ELKMYVENEL FKFPDDIVKH VNIKVNGSLV GHGELVSIED GYGIEISSWM VKE