SPAQ_SALTI
ID SPAQ_SALTI Reviewed; 86 AA.
AC P0A1L8; P40704; Q54011; Q54013; Q57117; Q57533;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Surface presentation of antigens protein SpaQ;
GN Name=spaQ; OrderedLocusNames=STY3012, t2791;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=s3333;
RX PubMed=7638176; DOI=10.1073/pnas.92.16.7252;
RA Li J., Ochman H., Groisman E.A., Boyd E.F., Solomon F., Nelson K.,
RA Selander R.K.;
RT "Relationship between evolutionary rate and cellular location among the
RT Inv/Spa invasion proteins of Salmonella enterica.";
RL Proc. Natl. Acad. Sci. U.S.A. 92:7252-7256(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Involved in a secretory pathway responsible for the surface
CC presentation of determinants needed for the entry of Salmonella species
CC into mammalian cells.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FliQ/MopD/SpaQ family. {ECO:0000305}.
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DR EMBL; U29363; AAC43862.1; -; Genomic_DNA.
DR EMBL; AL513382; CAD05996.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO70352.1; -; Genomic_DNA.
DR PIR; AE0851; AE0851.
DR RefSeq; NP_457283.1; NC_003198.1.
DR RefSeq; WP_000342503.1; NZ_WSUR01000005.1.
DR AlphaFoldDB; P0A1L8; -.
DR SMR; P0A1L8; -.
DR STRING; 220341.16503967; -.
DR EnsemblBacteria; AAO70352; AAO70352; t2791.
DR KEGG; stt:t2791; -.
DR KEGG; sty:STY3012; -.
DR PATRIC; fig|220341.7.peg.3066; -.
DR eggNOG; COG4794; Bacteria.
DR HOGENOM; CLU_164516_1_2_6; -.
DR OMA; IKLLAVF; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR InterPro; IPR002191; Bac_export_3.
DR InterPro; IPR006306; T3SS_HrpO.
DR PANTHER; PTHR34040; PTHR34040; 1.
DR Pfam; PF01313; Bac_export_3; 1.
DR PRINTS; PR00952; TYPE3IMQPROT.
DR TIGRFAMs; TIGR01403; fliQ_rel_III; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Virulence.
FT CHAIN 1..86
FT /note="Surface presentation of antigens protein SpaQ"
FT /id="PRO_0000129108"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 86 AA; 9359 MW; 3058D82ECE128892 CRC64;
MDDLVFAGNK ALYLVLILSG WPTIVATIIG LLVGLFQTVT QLQEQTLPFG IKLLGVCLCL
FLLSGWYGEV LLSYGRQVIF LALAKG