ID   SPAQ_SALTY              Reviewed;          86 AA.
AC   P0A1L7; P40704; Q54011; Q54013; Q57117; Q57533;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Surface presentation of antigens protein SpaQ;
GN   Name=spaQ; OrderedLocusNames=STM2889;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8404849; DOI=10.1002/j.1460-2075.1993.tb06056.x;
RA   Groisman E.A., Ochman H.;
RT   "Cognate gene clusters govern invasion of host epithelial cells by
RT   Salmonella typhimurium and Shigella flexneri.";
RL   EMBO J. 12:3779-3787(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=S4194;
RX   PubMed=7638176; DOI=10.1073/pnas.92.16.7252;
RA   Li J., Ochman H., Groisman E.A., Boyd E.F., Solomon F., Nelson K.,
RA   Selander R.K.;
RT   "Relationship between evolutionary rate and cellular location among the
RT   Inv/Spa invasion proteins of Salmonella enterica.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:7252-7256(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Involved in a secretory pathway responsible for the surface
CC       presentation of determinants needed for the entry of Salmonella species
CC       into mammalian cells.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FliQ/MopD/SpaQ family. {ECO:0000305}.
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DR   EMBL; X73525; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U29364; AAC43865.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL21769.1; -; Genomic_DNA.
DR   RefSeq; NP_461810.1; NC_003197.2.
DR   RefSeq; WP_000342503.1; NC_003197.2.
DR   PDB; 6PEM; EM; 3.50 A; 6/7/8/9=1-86.
DR   PDB; 6PEP; EM; 3.80 A; 6/7/8/9=1-86.
DR   PDB; 6Q14; EM; 3.80 A; 6/7/8/9=1-86.
DR   PDB; 6Q15; EM; 5.15 A; 6/7/8/9=1-86.
DR   PDB; 6Q16; EM; 4.10 A; 6/7/8/9=1-86.
DR   PDB; 7AGX; EM; 3.60 A; 1G/1H/1I/1J=1-86.
DR   PDB; 7AH9; EM; 3.30 A; 1G/1H/1I/1J=1-86.
DR   PDB; 7AHI; EM; 3.30 A; 1G/1H/1I/1J=1-86.
DR   PDBsum; 6PEM; -.
DR   PDBsum; 6PEP; -.
DR   PDBsum; 6Q14; -.
DR   PDBsum; 6Q15; -.
DR   PDBsum; 6Q16; -.
DR   PDBsum; 7AGX; -.
DR   PDBsum; 7AH9; -.
DR   PDBsum; 7AHI; -.
DR   AlphaFoldDB; P0A1L7; -.
DR   SMR; P0A1L7; -.
DR   DIP; DIP-59560N; -.
DR   IntAct; P0A1L7; 2.
DR   STRING; 99287.STM2889; -.
DR   PaxDb; P0A1L7; -.
DR   EnsemblBacteria; AAL21769; AAL21769; STM2889.
DR   GeneID; 1254412; -.
DR   KEGG; stm:STM2889; -.
DR   PATRIC; fig|99287.12.peg.3045; -.
DR   HOGENOM; CLU_164516_1_2_6; -.
DR   OMA; IKLLAVF; -.
DR   PhylomeDB; P0A1L7; -.
DR   BioCyc; SENT99287:STM2889-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR002191; Bac_export_3.
DR   InterPro; IPR006306; T3SS_HrpO.
DR   PANTHER; PTHR34040; PTHR34040; 1.
DR   Pfam; PF01313; Bac_export_3; 1.
DR   PRINTS; PR00952; TYPE3IMQPROT.
DR   TIGRFAMs; TIGR01403; fliQ_rel_III; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Virulence.
FT   CHAIN           1..86
FT                   /note="Surface presentation of antigens protein SpaQ"
FT                   /id="PRO_0000129109"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   86 AA;  9359 MW;  3058D82ECE128892 CRC64;
     MDDLVFAGNK ALYLVLILSG WPTIVATIIG LLVGLFQTVT QLQEQTLPFG IKLLGVCLCL
     FLLSGWYGEV LLSYGRQVIF LALAKG