ID   SPAS1_RAT               Reviewed;         281 AA.
AC   Q811V6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Spermatogenesis-associated serine-rich protein 1;
DE   AltName: Full=Spermatogenic serine-rich protein 1;
GN   Name=Spats1; Synonyms=Srsp1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=Wistar; TISSUE=Spermatocyte;
RX   PubMed=12826748; DOI=10.1159/000071043;
RA   Geisinger A., Dos Santos A., Benavente R., Wettstein R.;
RT   "Identification and characterization of SRSP1, a rat gene differentially
RT   expressed during spermatogenesis and coding for a serine stretch-containing
RT   protein.";
RL   Cytogenet. Genome Res. 98:249-254(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74; SER-77; SER-78;
RP   SER-79 AND SER-91, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE
RP   ANALYSIS].
RX   PubMed=16641100; DOI=10.1073/pnas.0600895103;
RA   Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A.;
RT   "Quantitative phosphoproteomics of vasopressin-sensitive renal cells:
RT   regulation of aquaporin-2 phosphorylation at two sites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006).
CC   -!- TISSUE SPECIFICITY: Detected in pachytene spermatocytes and round
CC       spermatids. {ECO:0000269|PubMed:12826748}.
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DR   EMBL; AY157978; AAN41641.1; -; mRNA.
DR   RefSeq; NP_852041.1; NM_181376.2.
DR   AlphaFoldDB; Q811V6; -.
DR   STRING; 10116.ENSRNOP00000038995; -.
DR   iPTMnet; Q811V6; -.
DR   PhosphoSitePlus; Q811V6; -.
DR   PaxDb; Q811V6; -.
DR   GeneID; 301255; -.
DR   KEGG; rno:301255; -.
DR   UCSC; RGD:631367; rat.
DR   CTD; 221409; -.
DR   RGD; 631367; Spats1.
DR   eggNOG; ENOG502S39M; Eukaryota.
DR   InParanoid; Q811V6; -.
DR   OrthoDB; 1532791at2759; -.
DR   PhylomeDB; Q811V6; -.
DR   PRO; PR:Q811V6; -.
DR   Proteomes; UP000002494; Unplaced.
DR   InterPro; IPR029165; SASRP1.
DR   PANTHER; PTHR35845; PTHR35845; 1.
DR   Pfam; PF15160; SASRP1; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..281
FT                   /note="Spermatogenesis-associated serine-rich protein 1"
FT                   /id="PRO_0000307696"
FT   REGION          1..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         53
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:A2RRY8"
FT   MOD_RES         71
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
FT   MOD_RES         74
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
FT   MOD_RES         77
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
FT   MOD_RES         78
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
FT   MOD_RES         79
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
FT   MOD_RES         91
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:16641100"
SQ   SEQUENCE   281 AA;  31133 MW;  DA7CFCBEB8D5A9CE CRC64;
     MEAARDAQHS DVLESKGCLA SRTSSHQNRR ASLSSDGTGL RVTDAPGLPR VMTPSDTASG
     LGQKTSSTSS SSSSSSSSSP SSSSSAQANR SLKVSLPEIQ KEKYPEEFSL LKSQTTDGQR
     PEWTFYPRFS SNIHTYHVGK QCFFNGVFRG NRKSVAERTV DKSLGKKKYD IDPRNGIPKL
     TPGDNPYMFP EQSKEFFKAG ATLPPVNFSL GPYEKKFDTF IPLEPLPQIP NLPFWEKEKA
     NNLKNEIKEV EDLDNWQAPM PFLHGFLSTA NRTITTCDQK V