ID   SPAT4_PANTR             Reviewed;         305 AA.
AC   Q6DMN8;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Spermatogenesis-associated protein 4;
GN   Name=SPATA4;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Liu S., Wang Z.;
RT   "Molecular cloning of SPATA4, a chimpanzee testis spermatocyte apoptosis-
RT   related gene.";
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in apoptosis regulation.
CC       {ECO:0000250|UniProtKB:Q8NEY3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8NEY3}.
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DR   EMBL; AY660661; AAT74558.1; -; mRNA.
DR   RefSeq; NP_001008990.1; NM_001008990.1.
DR   AlphaFoldDB; Q6DMN8; -.
DR   SMR; Q6DMN8; -.
DR   STRING; 9598.ENSPTRP00000028504; -.
DR   PaxDb; Q6DMN8; -.
DR   Ensembl; ENSPTRT00000030864; ENSPTRP00000028504; ENSPTRG00000016612.
DR   GeneID; 449514; -.
DR   KEGG; ptr:449514; -.
DR   CTD; 132851; -.
DR   VGNC; VGNC:695; SPATA4.
DR   eggNOG; ENOG502QU8V; Eukaryota.
DR   GeneTree; ENSGT00910000144159; -.
DR   HOGENOM; CLU_077979_1_0_1; -.
DR   InParanoid; Q6DMN8; -.
DR   OMA; SYQMHLP; -.
DR   OrthoDB; 1471531at2759; -.
DR   TreeFam; TF323506; -.
DR   Proteomes; UP000002277; Chromosome 4.
DR   Bgee; ENSPTRG00000016612; Expressed in testis and 14 other tissues.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IBA:GO_Central.
DR   Gene3D; 1.10.418.10; -; 1.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR010441; CH_2.
DR   InterPro; IPR036872; CH_dom_sf.
DR   Pfam; PF06294; CH_2; 1.
DR   PROSITE; PS50021; CH; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..305
FT                   /note="Spermatogenesis-associated protein 4"
FT                   /id="PRO_0000072103"
FT   DOMAIN          49..155
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00044"
SQ   SEQUENCE   305 AA;  34707 MW;  FDA9E3B7D5864101 CRC64;
     MAAAGREKGY VTQTAAALDK SPSLSPQLAA PIRGRPKKCL VYPHAPKSSR LSRSVLRWLQ
     GLDLSFFPRN INRDFSNGFL IAEIFCIYYP WELELSSFEN GTSLKVKLGN WAQLEKFLAR
     KKFKLPKELI HGTIHCKAGV PEILIEEVYT LLTHREIKSI QDDFVNFTDY SYQMRLPLVS
     RSTVSKSIKD NIRLSELLSN PNMLTNELKA EFLILLHMLQ RKLGRKLNPE WFDVKPTVGE
     VTLNHLPAQA SGRRYNLKVK RGRVVPVLPN IGSGGSSHRE IHVKQAGQHS YYSAMKPIRN
     MDKKP