SPA_SOLLC
ID SPA_SOLLC Reviewed; 159 AA.
AC K4BVL1;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2012, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Protein SPA, chloroplastic {ECO:0000303|PubMed:24372694};
DE AltName: Full=Sugar partition-affecting protein {ECO:0000303|PubMed:24372694};
DE Flags: Precursor;
GN Name=SPA {ECO:0000303|PubMed:24372694}; OrderedLocusNames=Solyc04g081320;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000312|Proteomes:UP000004994};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706;
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2]
RP FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=24372694; DOI=10.1111/tpj.12418;
RA Bermudez L., de Godoy F., Baldet P., Demarco D., Osorio S., Quadrana L.,
RA Almeida J., Asis R., Gibon Y., Fernie A.R., Rossi M., Carrari F.;
RT "Silencing of the tomato sugar partitioning affecting protein (SPA)
RT modifies sink strength through a shift in leaf sugar metabolism.";
RL Plant J. 77:676-687(2014).
CC -!- FUNCTION: Participates in determining harvest index (HI) by affecting
CC source-sink carbon distribution. Up-regulates the conversion of fixed
CC carbon to exportable sugars. {ECO:0000269|PubMed:24372694}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000269|PubMed:24372694}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in source leaves. Lower levels of
CC expression in fruits and stems. {ECO:0000269|PubMed:24372694}.
CC -!- MISCELLANEOUS: Its sequence is related to the DnaJ family but lacks the
CC J domain. The CR-type-like region is similar to CR-type zinc-fingers
CC and was shown to bind zinc. {ECO:0000250|UniProtKB:Q8GSJ6}.
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DR RefSeq; NP_001307325.1; NM_001320396.1.
DR AlphaFoldDB; K4BVL1; -.
DR STRING; 4081.Solyc04g081320.2.1; -.
DR PaxDb; K4BVL1; -.
DR PRIDE; K4BVL1; -.
DR GeneID; 101259741; -.
DR KEGG; sly:101259741; -.
DR eggNOG; ENOG502RY5W; Eukaryota.
DR HOGENOM; CLU_118793_0_0_1; -.
DR InParanoid; K4BVL1; -.
DR OrthoDB; 1437451at2759; -.
DR PhylomeDB; K4BVL1; -.
DR Proteomes; UP000004994; Unplaced.
DR ExpressionAtlas; K4BVL1; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0003756; F:protein disulfide isomerase activity; IBA:GO_Central.
DR GO; GO:0010206; P:photosystem II repair; IBA:GO_Central.
DR InterPro; IPR035272; DUF5351.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR Pfam; PF17302; DUF5351; 1.
DR SUPFAM; SSF57938; SSF57938; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Repeat; Thylakoid;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..47
FT /note="Chloroplast"
FT /evidence="ECO:0000305"
FT CHAIN 48..159
FT /note="Protein SPA, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000431977"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 92..99
FT /note="CXXCXGXG motif"
FT REPEAT 103..110
FT /note="CXXCXGXG motif"
FT REPEAT 126..133
FT /note="CXXCXGXG motif"
FT REPEAT 137..144
FT /note="CXXCXGXG motif"
FT REGION 85..145
FT /note="CR-type-like"
SQ SEQUENCE 159 AA; 17203 MW; 43D3591FFA5E61B2 CRC64;
MLTAPSLSRF KSPFISSPLK LPTLSSSFFT QKFHQTCRRR NSYPCIKAVD LDQNTVIAIT
VGVLSVAIGV GIPVFYETQI DNAAKRENTQ PCFPCTGTGA QKCRFCMGTG SVTVELGGGE
TEVSRCINCD GAGGLTCTTC QGSGIQPRYL DRREFKDDD
