ID   SPB5_XENTR              Reviewed;         379 AA.
AC   Q5M8J5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Serpin B5;
GN   Name=serpinb5;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May not exhibit serine protease inhibitory activity.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- SIMILARITY: Belongs to the serpin family. Ov-serpin subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC087996; AAH87996.1; -; mRNA.
DR   RefSeq; NP_001011282.1; NM_001011282.1.
DR   AlphaFoldDB; Q5M8J5; -.
DR   SMR; Q5M8J5; -.
DR   STRING; 8364.ENSXETP00000057493; -.
DR   MEROPS; I04.980; -.
DR   PaxDb; Q5M8J5; -.
DR   DNASU; 496735; -.
DR   Ensembl; ENSXETT00000057493; ENSXETP00000057493; ENSXETG00000027590.
DR   GeneID; 496735; -.
DR   KEGG; xtr:496735; -.
DR   CTD; 5268; -.
DR   Xenbase; XB-GENE-5802997; serpinb5.
DR   eggNOG; KOG2392; Eukaryota.
DR   HOGENOM; CLU_023330_0_2_1; -.
DR   InParanoid; Q5M8J5; -.
DR   OMA; TRTIIML; -.
DR   OrthoDB; 1124079at2759; -.
DR   PhylomeDB; Q5M8J5; -.
DR   TreeFam; TF352619; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027590; Expressed in skin of body and 2 other tissues.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:GO_Central.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:GO_Central.
DR   CDD; cd02057; serpinB5_maspin; 1.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR000240; Serpin_B9/Maspin.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   InterPro; IPR033836; SERPINB5_serpin_dom.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   PRINTS; PR00676; MASPIN.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted.
FT   CHAIN           1..379
FT                   /note="Serpin B5"
FT                   /id="PRO_0000372430"
FT   CARBOHYD        133
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        176
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        361
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   379 AA;  42907 MW;  BC5FF91B36A44CE5 CRC64;
     MDALRLANTA LAVDIFKKLC EKSATDNFVC SPLCISSSLS LIRKGSQGNT ASELEKALHF
     EKVKDPDFGF QLLSSDISKI SSANSLKLLK RVYVDNSIEC KKDFINSAKK PYPLELETID
     FKSQAEEART QINSSVKELT DGNFETVLNE GSCDENTKII MLGAASFKGK WVYTFNKSET
     KEMDFHINKK ETKPVQMMHL EARLSIGYIN ELKTMVLEMP FQSKHFSMLI LLPKDIEDDS
     TGLKKLEQDM TFEKYTHWTN PSMMANSKVK VSLPKFKMEN SYDLKDMLKS LGINDAFNEE
     ASDFSEMTES KGISISQAIQ KACIEVDEDG TESADVSMER RLMNKEEFLA DHPFIYILRH
     NKTRTIIMLG RYCGPSEAS