ID   SPC42_LACTC             Reviewed;         358 AA.
AC   C5DGS4;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Spindle pole body component SPC42;
GN   Name=SPC42; OrderedLocusNames=KLTH0D07854g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Forms a polymeric layer at the periphery of the spindle pole
CC       body (SPB) central plaque which has an essential function during SPB
CC       duplication and may facilitate attachment of the SPB to the nuclear
CC       membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, spindle pole body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPC42 family. {ECO:0000305}.
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DR   EMBL; CU928168; CAR22616.1; -; Genomic_DNA.
DR   RefSeq; XP_002553054.1; XM_002553008.1.
DR   AlphaFoldDB; C5DGS4; -.
DR   SMR; C5DGS4; -.
DR   STRING; 559295.C5DGS4; -.
DR   EnsemblFungi; CAR22616; CAR22616; KLTH0D07854g.
DR   GeneID; 8295287; -.
DR   KEGG; lth:KLTH0D07854g; -.
DR   eggNOG; ENOG502RYX7; Eukaryota.
DR   HOGENOM; CLU_056211_0_0_1; -.
DR   InParanoid; C5DGS4; -.
DR   OMA; HNHATHR; -.
DR   OrthoDB; 1453033at2759; -.
DR   Proteomes; UP000002036; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021611; Spc42.
DR   Pfam; PF11544; Spc42p; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..358
FT                   /note="Spindle pole body component SPC42"
FT                   /id="PRO_0000409210"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          135..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          310..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          82..140
FT                   /evidence="ECO:0000255"
FT   COILED          226..275
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        21..36
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   358 AA;  39523 MW;  D73E6BF533CD94D9 CRC64;
     MSPHTEGPLF AVLKNSRARP RPRESRLRRR VHKQMNISPT PKRYNSRGYE FPRSNDEAFH
     PFNREPPMVP SERILPEEYR VNSQMINKLI KQNKDLTQQL DRKQDEIDRL NVLVGSLRGK
     LIKYTELNKK LEQAAAGARQ SSPDDVLQVN RTRPREPPAG GTRLDDRLSD LYSKLETLTE
     LVVGSAAADR GARDHVHVPS AGATRTPSSG ASVSHRPLQP GAASEDDILT QESAELKGLE
     DQIDLLKRKL LIKRENELRK LSLNKELLDL MEKLDVSRPA GPVPSSSTPP HCDQCHKAAY
     QTAAANGGHG VPAGAGSGAG AGASMPSPRN PPYMSMAQVL ETPTPAHRSS HKPNDTLW