ID   SPC42_VANPO             Reviewed;         361 AA.
AC   A7TQU0;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Spindle pole body component SPC42;
GN   Name=SPC42; ORFNames=Kpol_460p24;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Forms a polymeric layer at the periphery of the spindle pole
CC       body (SPB) central plaque which has an essential function during SPB
CC       duplication and may facilitate attachment of the SPB to the nuclear
CC       membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, spindle pole body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPC42 family. {ECO:0000305}.
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DR   EMBL; DS480463; EDO15389.1; -; Genomic_DNA.
DR   RefSeq; XP_001643247.1; XM_001643197.1.
DR   AlphaFoldDB; A7TQU0; -.
DR   SMR; A7TQU0; -.
DR   STRING; 436907.A7TQU0; -.
DR   EnsemblFungi; EDO15389; EDO15389; Kpol_460p24.
DR   GeneID; 5543451; -.
DR   KEGG; vpo:Kpol_460p24; -.
DR   eggNOG; ENOG502RYX7; Eukaryota.
DR   HOGENOM; CLU_056211_0_0_1; -.
DR   InParanoid; A7TQU0; -.
DR   OMA; HNHATHR; -.
DR   OrthoDB; 1453033at2759; -.
DR   PhylomeDB; A7TQU0; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021611; Spc42.
DR   Pfam; PF11544; Spc42p; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..361
FT                   /note="Spindle pole body component SPC42"
FT                   /id="PRO_0000409211"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          308..361
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          61..125
FT                   /evidence="ECO:0000255"
FT   COILED          169..270
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        189..215
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..328
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   361 AA;  41196 MW;  1007FA8315CAB3F7 CRC64;
     MNISPTPKRY SSARSNRNEN NIPSMYSDPL YNDNMNQGGG IGHLGGPRNI GNVPTEKIVP
     EEYRLNSQMI NRLIKQNKEL NNKLNSKQDE INRLNSLVGS LRAKLIKYTE LNKKLNSDLQ
     NFQNSEIINN SITEDVNDYI QVPKKRSVTL GTSPDSMSTP TILKNSHPVD EKINKLNDKL
     DKLTNLVLEE KSSQSTTSNK STTPPVTSQP NLFFSKGPSD EDIMVKESVE LKNLEDQIDS
     LKRKLLIKRE NELRKISLNQ ELLELMDKLN LQNPSNAQQN FNNFDISPPL SRSNNESPEY
     CLECHNRHTS HSQSHNNHNI SNKQQNSQYH HQHQKESYLK KPDLPISNPL DTPTPLNKRP
     T