SPC42_YEAS2
ID SPC42_YEAS2 Reviewed; 363 AA.
AC C7GP31;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 13-OCT-2009, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Spindle pole body component SPC42;
GN Name=SPC42; ORFNames=C1Q_02039;
OS Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=574961;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAY291;
RX PubMed=19812109; DOI=10.1101/gr.091777.109;
RA Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA Pereira G.A.G.;
RT "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT bioethanol production.";
RL Genome Res. 19:2258-2270(2009).
CC -!- FUNCTION: Forms a polymeric layer at the periphery of the spindle pole
CC body (SPB) central plaque which has an essential function during SPB
CC duplication and may facilitate attachment of the SPB to the nuclear
CC membrane. {ECO:0000250}.
CC -!- SUBUNIT: Component of the SPC110 complex containing at least CMD1,
CC SPC29, SPC42 and SCP110. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC microtubule organizing center, spindle pole body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SPC42 family. {ECO:0000305}.
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DR EMBL; ACFL01000080; EEU07450.1; -; Genomic_DNA.
DR AlphaFoldDB; C7GP31; -.
DR SMR; C7GP31; -.
DR Proteomes; UP000008073; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR InterPro; IPR021611; Spc42.
DR Pfam; PF11544; Spc42p; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein.
FT CHAIN 1..363
FT /note="Spindle pole body component SPC42"
FT /id="PRO_0000409213"
FT REGION 160..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 62..136
FT /evidence="ECO:0000255"
FT COILED 248..297
FT /evidence="ECO:0000255"
FT COMPBIAS 168..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 213
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P36094"
FT MOD_RES 217
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P36094"
FT MOD_RES 284
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P36094"
FT MOD_RES 329
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P36094"
SQ SEQUENCE 363 AA; 42245 MW; E3B5731F219EA441 CRC64;
MNGSPTPKRY SSKSSRLYDD YYNIPYQYSN PTPMNRDYND VGSRINADKL VPEEYKRNTE
FINKAVQQNK ELNFKLREKQ NEIFELKKIA ETLRSKLEKY VDITKKLEDQ NLNLQIKISD
LEKKLSDANS TFKEMRFPKV KDPMVDDDPV SENYDQINVP KHRAPDATGN PRTTNKVSNT
SDQDSRLKAI ERTLSVLTNY VMRSEDGNND RMSPLPSPLN TISPINNRLN FQEPKRYNPT
VKVNPSDDDI MMYESAELKR VEEEIEELKR KILVRKKHDL RKLSLNNQLQ ELQSMMDGDD
NIKLDNVSKH NHATHRHSSQ SSRDYSPSSD ACLECSNDLY EKNRVKPENN MSETFATPTP
NNR
