SPC97_DICDI
ID SPC97_DICDI Reviewed; 1335 AA.
AC Q95ZG3; Q54MM8;
DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 2.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Spindle pole body component 97;
DE AltName: Full=DdSpc97;
DE Short=Spc97;
GN Name=spc97; ORFNames=DDB_G0285849;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 159-1335.
RC STRAIN=AX2;
RX PubMed=12018385; DOI=10.1078/0171-9335-00241;
RA Daunderer C., Graf R.O.;
RT "Molecular analysis of the cytosolic Dictyostelium gamma-tubulin complex.";
RL Eur. J. Cell Biol. 81:175-184(2002).
CC -!- FUNCTION: May be involved in microtubule nucleation.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome. Cytoplasm.
CC -!- SIMILARITY: Belongs to the TUBGCP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC47949.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AAFI02000082; EAL64459.1; -; Genomic_DNA.
DR EMBL; AJ318508; CAC47949.1; ALT_FRAME; mRNA.
DR RefSeq; XP_637962.1; XM_632870.1.
DR AlphaFoldDB; Q95ZG3; -.
DR SMR; Q95ZG3; -.
DR STRING; 44689.DDB0191247; -.
DR PaxDb; Q95ZG3; -.
DR PRIDE; Q95ZG3; -.
DR EnsemblProtists; EAL64459; EAL64459; DDB_G0285849.
DR GeneID; 8625315; -.
DR KEGG; ddi:DDB_G0285849; -.
DR dictyBase; DDB_G0285849; spc97.
DR eggNOG; KOG2001; Eukaryota.
DR HOGENOM; CLU_258805_0_0_1; -.
DR InParanoid; Q95ZG3; -.
DR OMA; IRIHNDF; -.
DR PhylomeDB; Q95ZG3; -.
DR PRO; PR:Q95ZG3; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0005813; C:centrosome; IDA:dictyBase.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000923; C:equatorial microtubule organizing center; IBA:GO_Central.
DR GO; GO:0000930; C:gamma-tubulin complex; IBA:GO_Central.
DR GO; GO:0008275; C:gamma-tubulin small complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IBA:GO_Central.
DR GO; GO:0051321; P:meiotic cell cycle; IBA:GO_Central.
DR GO; GO:0007020; P:microtubule nucleation; IBA:GO_Central.
DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0051225; P:spindle assembly; IBA:GO_Central.
DR Gene3D; 1.20.120.1900; -; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; PTHR19302; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Microtubule; Reference proteome.
FT CHAIN 1..1335
FT /note="Spindle pole body component 97"
FT /id="PRO_0000078116"
FT REGION 27..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1144..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 154571 MW; 3DD5A66B8627593B CRC64;
MKQNQPNLNV NLNNRLQQQQ LNQVAQQQLQ QQPLKNTKQN PINNQTNGIL NNKPITTSSN
IMNSDNILNN NNNNNTNKPS STFNFNITNT PPPPVNKQKP ITSSSTSKPS NTTTTTTTTT
TTTKPPSNSL PSSSSSKVKV NSLTSQNNNN NNSNTNTNMT TQPPTFNNLI KPQSLPSTTG
MNEIKNTPTR TTTTTSTQHT KYIKEDIVVK ENNNRISNMN NNNISGASGG TTFNSYNYLP
NNTLDNFINN SNTTTTTTNN NTNNNNNNNN NNNIINNIKQ QHELELLQQK HIEEMKILQN
EQLNQLKKQQ KKLNESDTDG SDDDDDDDDE YGENMNLSPR TLRELKNIQR LKNLEKFSPP
YLITKKTSPS IKTLPKFPEW TKERPFLNYG YLANISTNYT SLILPSKYEQ TKIQLSSIPN
YFREQILIED LLSTMIGIEG ECIHIGVVQE NEDDSLQSNL VSFVVEGEVD PSNNDLVQRI
LPLCSYYSFV NDFIQIRYAY EWGIINHSLC FSIDQLLKEY LVLVSQLEGQ LKSERLSLQR
MWFYLQPTIK TFEILYRVTS EIMRCNSHGV QVINLLLKLQ SKYSSDKKTD DLFHYLIKAT
TLPFLEMLDL WIHQGIIRDT YFEFMIEENT DLKRDNINRD FNDLYWEQRY QIRQDQIPKY
LQSHALKILT TGKYLNVVRE CNQSISQQQQ HNKSDNNNNN NNNVKLNSQQ QLLLLKLNTT
QQQQQQQLSS TSASMIPTTI IEYSKNENVY IDKIEKAYDY ASGILLNLLI NERHLISRLK
AIKHYFLLCK GDFFSHFMDT TYDELKKPLD QINMVKMNSL LQLSLRTSSI SEEDEFKDDL
ECEFIPYKLV DQLLNIININ NFNNPTTTTT TNTSSNNITA TTNTSSNNTT INTTVNTTLI
QSTSAHEVLK TNKLFGIESL AFNYNVGWPL SLIISRKSLI KYQIIFRHLF LCKHVEKVLV
DTWSQHQFRR SSYNKPGLST LLSFTHLLRH RMIHFLQNLE YYMMLEVLEP NWNKMKNSIK
TSKTVDDVIR IHNDFLETCL TECMLTDTKL VNILMKFMSL CITFANFTNE MMQDEKNIDT
EQIKKTISSS ENKFHAILKV LMDTLKSFSK TESNRHMIHL IHRLDYNGYY SHYFENNPNL
FKNKTSSSSN KSNNVSPPLE PRFSYQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
QQQQQQQQQQ QQQQQQKQNQ IQQQKQNQIQ QQQQQSRGST LPSNFSFQTA LQQQINTTSA
TTTTSNQSPH TLIDDLKKRA YGILDSNNTK KTLERTSSSP ALDNQSNSLP MTQSISQYAE
KLKNLRAVIK NDELK
