SPD13_HUMAN
ID SPD13_HUMAN Reviewed; 265 AA.
AC A0A494C0Z2;
DT 02-DEC-2020, integrated into UniProtKB/Swiss-Prot.
DT 05-JUN-2019, sequence version 1.
DT 03-AUG-2022, entry version 13.
DE RecName: Full=Putative speedy protein E13 {ECO:0000305};
GN Name=SPDYE13 {ECO:0000312|HGNC:HGNC:51509};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
CC -!- SIMILARITY: Belongs to the Speedy/Ringo family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC211486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A494C0Z2; -.
DR SMR; A0A494C0Z2; -.
DR MassIVE; A0A494C0Z2; -.
DR Ensembl; ENST00000652175.2; ENSP00000498801.1; ENSG00000286038.2.
DR MANE-Select; ENST00000612377.3; ENSP00000499200.1; NM_001382547.2; NP_001369476.1.
DR MANE-Select; ENST00000652175.2; ENSP00000498801.1; NM_001382563.2; NP_001369492.1.
DR GeneCards; SPDYE13; -.
DR HGNC; HGNC:51509; SPDYE13.
DR neXtProt; NX_A0A494C0Z2; -.
DR VEuPathDB; HostDB:ENSG00000286014; -.
DR VEuPathDB; HostDB:ENSG00000286038; -.
DR VEuPathDB; HostDB:ENSG00000286137; -.
DR Proteomes; UP000005640; Chromosome 7.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR GO; GO:0045737; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR InterPro; IPR020984; Speedy.
DR PANTHER; PTHR31156; PTHR31156; 2.
DR Pfam; PF11357; Spy1; 2.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..265
FT /note="Putative speedy protein E13"
FT /id="PRO_0000451620"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 265 AA; 31467 MW; 862E1C6AB59C70B0 CRC64;
MGQILGKIMM SHQPQPQEER SPQRSTSGYP LQEVVDDEVL GPSAPGVDPS PPRRSLGWKR
KRECLDESDD EPEKELAPEP EETWVAETLC GLKMKAKRRR VSLVLPEYYE AFNRLLEDPV
IKRLLAWDKD LRVSDKYLLA MVIAYFSRAG LPSWQYQRIH FFLALYLAND MEEDDEAPKQ
NIFYFLYEET RSHIPLLSEL WFQLCRYMNP RARKNCSQIA LFRKYRFHFF CSMRCRAWVS
LEELEEIQAY DPEHWVWARD RAHLS