ID   SPD14_HUMAN             Reviewed;         265 AA.
AC   P0DUD3;
DT   02-DEC-2020, integrated into UniProtKB/Swiss-Prot.
DT   02-DEC-2020, sequence version 1.
DT   03-AUG-2022, entry version 7.
DE   RecName: Full=Putative speedy protein E14 {ECO:0000305};
GN   Name=SPDYE14 {ECO:0000312|HGNC:HGNC:51510};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
CC   -!- SIMILARITY: Belongs to the Speedy/Ringo family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC211486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0DUD3; -.
DR   SMR; P0DUD3; -.
DR   MassIVE; P0DUD3; -.
DR   PeptideAtlas; P0DUD3; -.
DR   Ensembl; ENST00000651045.2; ENSP00000498497.1; ENSG00000286137.2.
DR   MANE-Select; ENST00000612377.3; ENSP00000499200.1; NM_001382547.2; NP_001369476.1.
DR   MANE-Select; ENST00000652175.2; ENSP00000498801.1; NM_001382563.2; NP_001369492.1.
DR   GeneCards; SPDYE14; -.
DR   HGNC; HGNC:51510; SPDYE14.
DR   neXtProt; NX_P0DUD3; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   InterPro; IPR020984; Speedy.
DR   PANTHER; PTHR31156; PTHR31156; 2.
DR   Pfam; PF11357; Spy1; 2.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..265
FT                   /note="Putative speedy protein E14"
FT                   /id="PRO_0000451621"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..68
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   265 AA;  31467 MW;  862E1C6AB59C70B0 CRC64;
     MGQILGKIMM SHQPQPQEER SPQRSTSGYP LQEVVDDEVL GPSAPGVDPS PPRRSLGWKR
     KRECLDESDD EPEKELAPEP EETWVAETLC GLKMKAKRRR VSLVLPEYYE AFNRLLEDPV
     IKRLLAWDKD LRVSDKYLLA MVIAYFSRAG LPSWQYQRIH FFLALYLAND MEEDDEAPKQ
     NIFYFLYEET RSHIPLLSEL WFQLCRYMNP RARKNCSQIA LFRKYRFHFF CSMRCRAWVS
     LEELEEIQAY DPEHWVWARD RAHLS