ID   SPD18_HUMAN             Reviewed;         352 AA.
AC   P0DV79;
DT   25-MAY-2022, integrated into UniProtKB/Swiss-Prot.
DT   25-MAY-2022, sequence version 1.
DT   03-AUG-2022, entry version 2.
DE   RecName: Full=Speedy protein E18 {ECO:0000305};
GN   Name=SPDYE18 {ECO:0000312|HGNC:HGNC:51514};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
CC   -!- SIMILARITY: Belongs to the Speedy/Ringo family. {ECO:0000305}.
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DR   EMBL; AC007000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000510091.4; ENSP00000509550.1; ENSG00000205482.11.
DR   MANE-Select; ENST00000510091.4; ENSP00000509550.1; NM_001394953.1; NP_001381882.1.
DR   HGNC; HGNC:51514; SPDYE18.
DR   GeneTree; ENSGT00940000154173; -.
DR   Proteomes; UP000005640; Unplaced.
DR   InterPro; IPR020984; Speedy.
DR   PANTHER; PTHR31156; PTHR31156; 1.
DR   Pfam; PF11357; Spy1; 2.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..352
FT                   /note="Speedy protein E18"
FT                   /id="PRO_0000455536"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   352 AA;  41835 MW;  5DDE346E1CA2BFD6 CRC64;
     MDRTKTRFRK RGQITGKITT SRQPHPQNEQ SLQRSTSGYP LQEVVDDEVL GPSAPGVDPS
     PPCRSLGWKR KKEWSDESEE EPEKELAPEP EETWVVEMLC GLKMKLKQQR VSPILPEHHK
     DFNSQLAPGV DPSPPHRSFC WKRKREWWDE SEESLEEEPR KVLAPEPEEI WVAEMLCGLK
     MKLKRRRVSL VLPEHHEAFN RLLEDPVIKR FLAWDKDLRV SDKYLLAMVI AYFSRAGLPS
     WQYQRIHFFL ALYLANDMEE DDEDPKQNIF YFLYGKTRSR IPLVRNRRFQ LCRCLNPRAR
     KNRSQIALFQ KLRFQFFCSM SGRAWVSREE LEEIQAYDPE HWVWARDRAR LS