SPD1_ARABI
ID SPD1_ARABI Reviewed; 79 AA.
AC P46802;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 41.
DE RecName: Full=Spidroin-1;
DE AltName: Full=Dragline silk fibroin 1;
DE Flags: Fragment;
OS Araneus bicentenarius (Giant lichen orbweaver).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Araneoidea; Araneidae; Araneus.
OX NCBI_TaxID=29013;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=8120021; DOI=10.1016/s0021-9258(17)37425-2;
RA Beckwitt R., Arcidiacono S.;
RT "Sequence conservation in the C-terminal region of spider silk proteins
RT (Spidroin) from Nephila clavipes (Tetragnathidae) and Araneus bicentenarius
RT (Araneidae).";
RL J. Biol. Chem. 269:6661-6663(1994).
CC -!- FUNCTION: Spiders' major ampullate silk possesses unique
CC characteristics of strength and elasticity. Fibroin consists of
CC pseudocrystalline regions of antiparallel beta-sheet interspersed with
CC elastic amorphous segments.
CC -!- SUBUNIT: Major subunit, with spidroin 2, of the dragline silk.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC -!- DOMAIN: Highly repetitive protein characterized by regions of
CC polyalanine and glycine-rich repeating units.
CC -!- SIMILARITY: Belongs to the silk fibroin family. {ECO:0000305}.
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DR EMBL; U03847; AAA17673.1; -; Unassigned_DNA.
DR PIR; B54368; B54368.
DR AlphaFoldDB; P46802; -.
DR SMR; P46802; -.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.10.1350; -; 1.
DR InterPro; IPR021001; Spidroin_C.
DR InterPro; IPR038542; Spidroin_C_sf.
DR Pfam; PF11260; Spidroin_MaSp; 1.
PE 3: Inferred from homology;
KW Secreted; Silk protein.
FT CHAIN <1..79
FT /note="Spidroin-1"
FT /id="PRO_0000221445"
FT NON_TER 1
SQ SEQUENCE 79 AA; 7763 MW; 22FBC5BF0559792D CRC64;
RVSSAVSSLV SSGPTTPAAL SNTISSAVSQ ISASNPGLSG CDVLVQALLE VVSALVHILG
SSSVGQINYG ASAQYAQMV