SPD9_HUMAN
ID SPD9_HUMAN Reviewed; 265 AA.
AC A0A494C191;
DT 02-DEC-2020, integrated into UniProtKB/Swiss-Prot.
DT 05-JUN-2019, sequence version 1.
DT 03-AUG-2022, entry version 15.
DE RecName: Full=Putative speedy protein E9 {ECO:0000305};
GN Name=SPDYE9 {ECO:0000312|HGNC:HGNC:45034};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
CC -!- SIMILARITY: Belongs to the Speedy/Ringo family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC211476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006716273.1; XM_006716210.3.
DR RefSeq; XP_006716275.1; XM_006716212.3.
DR RefSeq; XP_006726497.1; XM_006726434.3.
DR RefSeq; XP_016868377.1; XM_017012888.1.
DR RefSeq; XP_016868422.1; XM_017012933.1.
DR RefSeq; XP_016885939.1; XM_017030450.1.
DR AlphaFoldDB; A0A494C191; -.
DR SMR; A0A494C191; -.
DR MassIVE; A0A494C191; -.
DR Ensembl; ENST00000575125.6; ENSP00000498945.1; ENSG00000262461.7.
DR MANE-Select; ENST00000333385.11; ENSP00000498819.1; NM_001382525.2; NP_001369454.1.
DR MANE-Select; ENST00000340073.9; ENSP00000498510.1; NM_001351349.3; NP_001338278.1.
DR MANE-Select; ENST00000575125.6; ENSP00000498945.1; NM_001382554.3; NP_001369483.1.
DR MANE-Select; ENST00000671986.3; ENSP00000501236.1; NM_001351351.3; NP_001338280.1.
DR MANE-Select; ENST00000691996.1; ENSP00000508934.1; NM_001382505.2; NP_001369434.1.
DR GeneCards; SPDYE9; -.
DR HGNC; HGNC:45034; SPDYE9.
DR neXtProt; NX_A0A494C191; -.
DR VEuPathDB; HostDB:ENSG00000262461; -.
DR VEuPathDB; HostDB:ENSG00000273520; -.
DR VEuPathDB; HostDB:ENSG00000286228; -.
DR Proteomes; UP000005640; Chromosome 7.
DR Bgee; ENSG00000262461; Expressed in stromal cell of endometrium and 97 other tissues.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR GO; GO:0045737; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR InterPro; IPR020984; Speedy.
DR PANTHER; PTHR31156; PTHR31156; 2.
DR Pfam; PF11357; Spy1; 2.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..265
FT /note="Putative speedy protein E9"
FT /id="PRO_0000451618"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 265 AA; 31441 MW; BF4F3DD204B75202 CRC64;
MGQILGKIMM SHQPQPQEER SPQRSTSGYP LQEVVDDEVS GPSAPGVDPS PPRRSLGWKR
KRECLDESDD EPEKELAPEP EETWVAETLC GLKMKAKRRR VSLVLPEYYE AFNRLLEDPV
IKRLLAWDKD LRVSDKYLLA MVIAYFSRAG LPSWQYQRIH FFLALYLAND MEEDDEAPKQ
NIFYFLYEET RSHIPLLSEL WFQLCRYMNP RARKNCSQIA LFRKYRFHFF CSMRCRAWVS
LEELEEIQAY DPEHWVWARD RAHLS