ID   SPEM1_BOVIN             Reviewed;         313 AA.
AC   Q32LJ5;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Spermatid maturation protein 1;
GN   Name=SPEM1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper cytoplasm removal during spermatogenesis.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}. Cytoplasm {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI09547.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC109546; AAI09547.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001073054.2; NM_001079586.2.
DR   AlphaFoldDB; Q32LJ5; -.
DR   STRING; 9913.ENSBTAP00000042433; -.
DR   PaxDb; Q32LJ5; -.
DR   PRIDE; Q32LJ5; -.
DR   GeneID; 511321; -.
DR   KEGG; bta:511321; -.
DR   CTD; 374768; -.
DR   eggNOG; ENOG502ST8J; Eukaryota.
DR   InParanoid; Q32LJ5; -.
DR   OrthoDB; 1151298at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR031368; SPEM1_N.
DR   Pfam; PF15670; Spem1; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Developmental protein; Differentiation; Membrane;
KW   Reference proteome; Spermatogenesis; Transmembrane; Transmembrane helix.
FT   CHAIN           1..313
FT                   /note="Spermatid maturation protein 1"
FT                   /id="PRO_0000307805"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          71..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          97..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          243..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          291..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          263..289
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        105..119
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   313 AA;  35332 MW;  A2AD46B7BA94FF61 CRC64;
     MAMAERPRPG WASYHNPNTN SCQDLGNSIL LLLGLIICIN IGINMVTLLW RRLRGFLHQV
     FRVICEKEAS KLRSPGKQTQ PSKHSSPAVH LRCTMDAVKM TVTPPPTRRR HRRGSSSRRA
     RRPVAWAPDT DDDDDEKPPH QHTAACSHNW DYPEDWEGLQ TAQRFWTPWA QDTLEPPTQT
     IRFQQTIEGR PLKREMQSDL GLEAYVYPVN PPLPSPQILS HKNSGGGAGA GAQAEQEQCA
     PAEPPILGPA NVPDIPRRRS SGRVTYDARD VRRRLRELTR EVEALSHCYP LASGSSTAEG
     TRKDWVYRSM TER