ID   SPH2_HALSA              Reviewed;         667 AA.
AC   Q9HHY2;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Smc-like protein Sph2;
GN   Name=sph2; OrderedLocusNames=VNG_6173C;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OG   Plasmid pNRC200.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: May play a role in replication. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Sph1/Sph2 family. {ECO:0000305}.
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DR   EMBL; AE004438; AAG20841.1; -; Genomic_DNA.
DR   RefSeq; WP_010904054.1; NZ_BK010831.1.
DR   AlphaFoldDB; Q9HHY2; -.
DR   SMR; Q9HHY2; -.
DR   EnsemblBacteria; AAG20841; AAG20841; VNG_6173C.
DR   GeneID; 5954712; -.
DR   GeneID; 62888111; -.
DR   KEGG; hal:VNG_6173C; -.
DR   PATRIC; fig|64091.14.peg.2198; -.
DR   HOGENOM; CLU_409187_0_0_2; -.
DR   InParanoid; Q9HHY2; -.
DR   OMA; SFMTFDQ; -.
DR   OrthoDB; 29236at2157; -.
DR   PhylomeDB; Q9HHY2; -.
DR   Proteomes; UP000000554; Plasmid pNRC200.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Plasmid; Reference proteome.
FT   CHAIN           1..667
FT                   /note="Smc-like protein Sph2"
FT                   /id="PRO_0000409227"
FT   COILED          153..295
FT                   /evidence="ECO:0000255"
FT   COILED          355..517
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   667 AA;  75727 MW;  215A8D9CFCD4318C CRC64;
     METNAVSLIY RCRVGERMSQ HDTDGRVSVY AENIGGISQC DVTFKPGVNV LRGRNATGRT
     SLLNGLAGVL GGTAPVLKGD EQEAEVRLEF NGTTYDQQYT RKNGTVQAAG QPVTERRDLV
     DLFVCLTAEN PARRAIVQDG NLRDVIMRPV DTGSIQRRIE DLQSERNRIG QRIRAIEDDL
     DQRTSLTSRK TTLVSDLDEC DQEIEELRNQ LEQFDADPEE AEEIEQALTS LEERKQELES
     ITNRIRTQED TREALRDEQS ELQTEREAIE TSEEELKRIE TRLSELTSRE RSLATTINDL
     SAIVDFNEDL VSNADSDLLR SGDAAESPVS KLNPMSETVE CWTCGTEVER NRIAGRLDDL
     RDLVDEKRTE RSEVQTEIEE LRESQQELQE VIHRRDEIGQ RLSEISSEIA QRDQTLESLS
     EEREDVHQRL SELEEFVSER EALQESELTE QYQQLSELEY QRGQLEEELS AVREELAELD
     RLENERDQLQ AQQDEIQAEL VSQRTQIRDL EESAITAFND HMEEILDVLR YKNIARVWIE
     RKEGAEFNSS HGGYRGGSAT KFELHVVRET DEGRGYEDTV QSLSESEREV VGLVVALAGY
     LVHDVYEVIP MMLLDSLEAI DADRIAALVD YFADYAPYLI VALLPEDADA LGGDETSVVP
     ASFASEE