ID   SPHR_AMEPV              Reviewed;        1003 AA.
AC   P29815;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   23-FEB-2022, entry version 62.
DE   RecName: Full=Spheroidin;
GN   OrderedLocusNames=AMV187; ORFNames=G5;
OS   Amsacta moorei entomopoxvirus (AmEPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Entomopoxvirinae; Betaentomopoxvirus.
OX   NCBI_TaxID=28321;
OH   NCBI_TaxID=340055; Amsacta.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, AND
RP   ACETYLATION AT SER-2.
RX   PubMed=1545219; DOI=10.1099/0022-1317-73-3-559;
RA   Banville M., Dumas F., Trifiro S., Arif B., Richardson C.;
RT   "The predicted amino acid sequence of the spheroidin protein from Amsacta
RT   moorei entomopoxvirus: lack of homology between major occlusion body
RT   proteins of different poxviruses.";
RL   J. Gen. Virol. 73:559-566(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX   PubMed=1942245; DOI=10.1128/jvi.65.12.6516-6527.1991;
RA   Hall R.L., Moyer R.W.;
RT   "Identification, cloning, and sequencing of a fragment of Amsacta moorei
RT   entomopoxvirus DNA containing the spheroidin gene and three vaccinia virus-
RT   related open reading frames.";
RL   J. Virol. 65:6516-6527(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10936094; DOI=10.1006/viro.2000.0449;
RA   Bawden A.L., Glassberg K.J., Diggans J., Shaw R., Farmerie W., Moyer R.W.;
RT   "Complete genomic sequence of the Amsacta moorei entomopoxvirus: analysis
RT   and comparison with other poxviruses.";
RL   Virology 274:120-139(2000).
CC   -!- FUNCTION: Major component of viral occlusion bodies, the protective
CC       complexes in which the virions are embedded in the cytoplasm of their
CC       insect hosts.
CC   -!- SUBUNIT: May form disulfide-bond-linked aggregates.
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DR   EMBL; M75889; AAA42378.1; -; Genomic_DNA.
DR   EMBL; M77182; AAA42383.1; -; Genomic_DNA.
DR   EMBL; AF250284; AAG02893.1; -; Genomic_DNA.
DR   PIR; JQ1436; PYVZAM.
DR   RefSeq; NP_064969.1; NC_002520.1.
DR   iPTMnet; P29815; -.
DR   GeneID; 1494777; -.
DR   KEGG; vg:1494777; -.
DR   Proteomes; UP000000872; Genome.
DR   GO; GO:0039679; C:viral occlusion body; IEA:UniProtKB-KW.
DR   InterPro; IPR008843; Spheroidin.
DR   Pfam; PF05541; Spheroidin; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Disulfide bond; Late protein;
KW   Reference proteome; Viral occlusion body.
FT   INIT_MET        1
FT                   /note="Removed; by host"
FT   CHAIN           2..1003
FT                   /note="Spheroidin"
FT                   /id="PRO_0000099759"
FT   REGION          953..979
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        953..974
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylserine; by host"
FT                   /evidence="ECO:0000269|PubMed:1545219"
SQ   SEQUENCE   1003 AA;  114870 MW;  6529F7767B058308 CRC64;
     MSNVPLATKT IRKLSNRKYE IKIYLKDENT CFERVVDMVV PLYDVCNETS GVTLESCSPN
     IEVIELDNTH VRIKVHGDTL KEMCFELLFP CNVNEAQVWK YVSRLLLDNV SHNDVKYKLA
     NFRLTLNGKH LKLKEIDQPL FIYFVDDLGN YGLITKENIQ NNNLQVNKDA SFITIFPQYA
     YICLGRKVYL NEKVTFDVTT DATNITLDFN KSVNIAVSFL DIYYEVNNNE QKDLLKDLLK
     RYGEFEVYNA DTGLIYAKNL SIKNYDTVIQ VERLPVNLKV RAYTKDENGR NLCLMKITSS
     TEVDPEYVTS NNALLGTLRV YKKFDKSHLK IVMHNRGSGN VFPLRSLYLE LSNVKGYPVK
     ASDTSRLDVG IYKLNKIYVD NDENKIILEE IEAEYRCGRQ VFHERVKLNK HQCKYTPKCP
     FQFVVNSPDT TIHLYGISNV CLKPKVPKNL RLWGWILDCD TSRFIKHMAD GSDDLDLDVR
     LNRNDICLKQ AIKQHYTNVI ILEYANTYPN CTLSLGNNRF NNVFDMNDNK TISEYTNFTK
     SRQDLNNMSC ILGINIGNSV NISSLPGWVT PHEAKILRSG CARVREFCKS FCDLSNKRFY
     AMARDLVSLL FMCNYVNIEI NEAVCEYPGY VILFARAIKV INDLLLINGV DNLAGYSISL
     PIHYGSTEKT LPNEKYGGVD KKFKYLFLKN KLKDLMRDAD FVQPPLYIST YFRTLLDAPP
     TDNYEKYLVD SSVQSQDVLQ GLLNTCNTID TNARVASSVI GYVYEPCGTS EHKIGSEALC
     KMAKEASRLG NLGLVNRINE SNYNKCNKYG YRGVYENNKL KTKYYREIFD CNPNNNNELI
     SRYGYRIMDL HKIGEIFANY DESESPCERR CHYLEDRGLL YGPEYVHHRY QESCTPNTFG
     NNTNCVTRNG EQHVYENSCG DNATCGRRTG YGRRSRDEWN DYRKPHVYDN CADANSSSSD
     SCSDSSSSSE SESDSDGCCD TDASLDSDIE NCYQNPSKCD AGC