SPI2A_VACCC
ID SPI2A_VACCC Reviewed; 116 AA.
AC P20841;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 29-SEP-2021, entry version 84.
DE RecName: Full=Putative serine proteinase inhibitor 2 homolog first part;
GN ORFNames=B13R;
OS Vaccinia virus (strain Copenhagen) (VACV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX NCBI_TaxID=10249;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA Paoletti E.;
RT "The complete DNA sequence of vaccinia virus.";
RL Virology 179:247-266(1990).
RN [2]
RP COMPLETE GENOME.
RA Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA Paoletti E.;
RT "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL Virology 179:517-563(1990).
CC -!- SIMILARITY: Belongs to the serpin family. Poxviruses subfamily.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. In contrast to strain
CC WR, where the SPI-2 inhibitor may be involved in the regulation of the
CC complement cascade, in strain Copenhagen it is interrupted by a stop
CC codon and thus is found in two parts. {ECO:0000305}.
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DR EMBL; M35027; AAA48210.1; -; Genomic_DNA.
DR SMR; P20841; -.
DR MEROPS; I04.028; -.
DR Proteomes; UP000008269; Genome.
DR Gene3D; 3.30.497.10; -; 1.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR Pfam; PF00079; Serpin; 1.
DR SUPFAM; SSF56574; SSF56574; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..116
FT /note="Putative serine proteinase inhibitor 2 homolog first
FT part"
FT /id="PRO_0000094142"
SQ SEQUENCE 116 AA; 12849 MW; 8A2E888330749B74 CRC64;
MKGENVFISP ASISSVLTIL YYGANGSTAE QLSKYVETEE NTDKVSAQNI SFKSINKVYG
RYSAVFKDFF LGKIGDKFQT VDFTDCRTID AINKCVDIFT EGKINPLLDE PLSPSN