ID   SPI2B_VACCC             Reviewed;         222 AA.
AC   P20842;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 83.
DE   RecName: Full=Putative serine proteinase inhibitor 2 homolog second part;
GN   ORFNames=B14R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   COMPLETE GENOME.
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- SIMILARITY: Belongs to the serpin family. Poxviruses subfamily.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. In contrast to strain
CC       WR, where the SPI-2 inhibitor may be involved in the regulation of the
CC       complement cascade, in strain Copenhagen it is interrupted by a stop
CC       codon and thus is found in two parts. {ECO:0000305}.
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DR   EMBL; M35027; AAA48211.1; -; Genomic_DNA.
DR   PIR; D42527; WMVZB4.
DR   SMR; P20842; -.
DR   MEROPS; I04.049; -.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..222
FT                   /note="Putative serine proteinase inhibitor 2 homolog
FT                   second part"
FT                   /id="PRO_0000094143"
SQ   SEQUENCE   222 AA;  24911 MW;  1E4BDF48A193067B CRC64;
     MNHCLLAISA VYFKAKWLTP FEKEFTSDYP FYVSPTEMVD VSMMSMYGEL FNHASVKESF
     GNFSIIELPY VGDTSMMVIL PDKIDGLESI EQNLTDTNFK KWCNSLDAMF IDVHIPKFKV
     TGSYNLVDTL VKSGLTEVFG STGDYSNMCN LDVSVDAMIH KTYIDVNEEY TEAAAATCAL
     VSDCASTITN EFCVDHPFIY VIRHVDGKIL FVGRYCSPTT NC