ID   SPINW_CHICK             Reviewed;         262 AA.
AC   Q90WG2;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Spindlin-W;
DE            Short=chSpin-W;
GN   Name=SPINW;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Ovary;
RX   PubMed=11419793; DOI=10.1023/a:1016694513051;
RA   Itoh Y., Hori T., Saitoh H., Mizuno S.;
RT   "Chicken spindlin genes on W and Z chromosomes: transcriptional expression
RT   of both genes and dynamic behavior of spindlin in interphase and mitotic
RT   cells.";
RL   Chromosome Res. 9:283-299(2001).
CC   -!- FUNCTION: May play a role in mitosis. {ECO:0000269|PubMed:11419793}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11419793}.
CC   -!- TISSUE SPECIFICITY: Expressed predominantly in ovarian granulosa and
CC       thecal cell. {ECO:0000269|PubMed:11419793}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in early embryo.
CC       {ECO:0000269|PubMed:11419793}.
CC   -!- SIMILARITY: Belongs to the SPIN/STSY family. {ECO:0000305}.
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DR   EMBL; AB047852; BAB59129.1; -; mRNA.
DR   RefSeq; NP_989522.1; NM_204191.1.
DR   RefSeq; XP_015155935.1; XM_015300449.1.
DR   AlphaFoldDB; Q90WG2; -.
DR   SMR; Q90WG2; -.
DR   Ensembl; ENSGALT00000077692; ENSGALP00000048979; ENSGALG00000040704.
DR   GeneID; 374014; -.
DR   KEGG; gga:374014; -.
DR   CTD; 374014; -.
DR   VEuPathDB; HostDB:geneid_374014; -.
DR   GeneTree; ENSGT00950000182925; -.
DR   InParanoid; Q90WG2; -.
DR   OMA; NMASSKG; -.
DR   OrthoDB; 1027563at2759; -.
DR   PRO; PR:Q90WG2; -.
DR   Proteomes; UP000000539; Chromosome W.
DR   Bgee; ENSGALG00000040704; Expressed in ovary and 8 other tissues.
DR   GO; GO:0005730; C:nucleolus; IDA:AgBase.
DR   GO; GO:0016605; C:PML body; IDA:AgBase.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
DR   Gene3D; 2.80.10.70; -; 1.
DR   InterPro; IPR003671; SPIN/Ssty.
DR   InterPro; IPR042567; SPIN/Ssty_sf.
DR   InterPro; IPR029565; Spindlin-1.
DR   PANTHER; PTHR10405; PTHR10405; 1.
DR   PANTHER; PTHR10405:SF15; PTHR10405:SF15; 1.
DR   Pfam; PF02513; Spin-Ssty; 3.
PE   2: Evidence at transcript level;
KW   Cell cycle; Nucleus; Reference proteome.
FT   CHAIN           1..262
FT                   /note="Spindlin-W"
FT                   /id="PRO_0000259593"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..40
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   262 AA;  29781 MW;  CA0755CE6C03B9A6 CRC64;
     MKTPFGKSPA QRSRADAGHT RVSASMMKKR TSHKKHRNNV GPSKPISQPR RNIVGCRIQH
     GWKEGSGPIT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL ELHKDERVSA LEVLPDRVAS
     SRISDAHLAD TMIGKAVEHM FETEDGSKDE WRGMVLARAP IMNTWFYITY EKDPVLYMYQ
     LLDDYKEGDL RIMPDSNDSP PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP
     SVYFIKFDDD FHIYVYDLVK TS