ID   SPI_STRAJ               Reviewed;         303 AA.
AC   Q53308;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Sporulation regulatory protein;
GN   Name=spi;
OS   Streptomyces azureus.
OG   Plasmid pSA1.1.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=146537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14921 / DSM 40106 / CBS 467.68 / ETH 28555 / JCM 4564 / NBRC
RC   12744 / NRRL B-2655 / VKM Ac-719;
RX   PubMed=7763542; DOI=10.1271/bbb.57.438;
RA   Tomura T., Kishino H., Doi K., Hara T., Kuhara S., Ogata S.;
RT   "Sporulation-inhibitory gene in pock-forming plasmid pSA1.1 of Streptomyces
RT   azureus.";
RL   Biosci. Biotechnol. Biochem. 57:438-443(1993).
CC   -!- FUNCTION: Involved in sporulation inhibition and pock formation.
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DR   EMBL; S58719; AAC60434.1; -; Genomic_DNA.
DR   PIR; JC1485; JC1485.
DR   AlphaFoldDB; Q53308; -.
DR   SMR; Q53308; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01580; FtsK_SpoIIIE; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50901; FTSK; 1.
PE   4: Predicted;
KW   ATP-binding; Nucleotide-binding; Plasmid.
FT   CHAIN           1..303
FT                   /note="Sporulation regulatory protein"
FT                   /id="PRO_0000098327"
FT   DOMAIN          26..213
FT                   /note="FtsK"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00289"
FT   BINDING         43..50
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   303 AA;  32513 MW;  400B6D3B45A573BE CRC64;
     MTCCAGCGSA ARPARMAWRS GRCARTGRLR AGLRKAPMAL TLGANHSGKS MYQRNLIKGL
     AQLPVALVGI DCKRGVEQAA FAPRLSALVT TPDDAASLLG VLVAEMEGRF DLLSRHGVSD
     LWELPAEVRP VPVVVLVDEV AELFLISSKK DEERRERIVT ALIRLAQMAR AIGIHLEICG
     QRFGSDLGKG ATMLRAQLTG RVVHRVNDKQ TAEMGLADVA PDAVPAASLI PMNRPGTAVA
     ADPSGGWSKI RTPETSRDEV VAVCREFAHL IPDLPFLEPF RPRVPAEVPA AGPSMVKPRP
     LTE