SPL10_ARATH
ID SPL10_ARATH Reviewed; 396 AA.
AC Q8S9L0; Q2V4K9; Q9FZJ9; Q9ZW53;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Squamosa promoter-binding-like protein 10;
GN Name=SPL10; OrderedLocusNames=At1g27370; ORFNames=F17L21.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=10524240; DOI=10.1016/s0378-1119(99)00308-x;
RA Cardon G.H., Hoehmann S., Klein J., Nettesheim K., Saedler H., Huijser P.;
RT "Molecular characterization of the Arabidopsis SBP-box genes.";
RL Gene 237:91-104(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP INDUCTION.
RX PubMed=12202040; DOI=10.1016/s0092-8674(02)00863-2;
RA Rhoades M.W., Reinhart B.J., Lim L.P., Burge C.B., Bartel B., Bartel D.P.;
RT "Prediction of plant microRNA targets.";
RL Cell 110:513-520(2002).
RN [6]
RP DEVELOPMENTAL STAGE.
RX PubMed=14573523; DOI=10.1242/dev.00842;
RA Schmid M., Uhlenhaut N.H., Godard F., Demar M., Bressan R., Weigel D.,
RA Lohmann J.U.;
RT "Dissection of floral induction pathways using global expression
RT analysis.";
RL Development 130:6001-6012(2003).
CC -!- FUNCTION: Trans-acting factor that binds specifically to the consensus
CC nucleotide sequence 5'-TNCGTACAA-3'. {ECO:0000250}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed constitutively during plant development,
CC weak increase during flowering. {ECO:0000269|PubMed:10524240,
CC ECO:0000269|PubMed:14573523}.
CC -!- INDUCTION: Negatively regulated by microRNAs miR156 and miR157.
CC {ECO:0000305|PubMed:12202040}.
CC -!- DOMAIN: The SBP-type zinc finger is required for the binding to DNA.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF99748.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ011636; CAB56588.1; -; Genomic_DNA.
DR EMBL; AJ011637; CAB56589.1; -; mRNA.
DR EMBL; AC004557; AAF99748.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE30814.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30815.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30816.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30817.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61026.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61027.1; -; Genomic_DNA.
DR EMBL; AY074853; AAL75905.1; -; mRNA.
DR EMBL; AY142028; AAM98292.1; -; mRNA.
DR PIR; T52596; T52596.
DR RefSeq; NP_001031096.2; NM_001036019.3.
DR RefSeq; NP_001077605.1; NM_001084136.1.
DR RefSeq; NP_001319090.1; NM_001332754.1.
DR RefSeq; NP_001323271.1; NM_001332755.1.
DR RefSeq; NP_174057.2; NM_102499.4.
DR RefSeq; NP_973921.1; NM_202192.2.
DR AlphaFoldDB; Q8S9L0; -.
DR SMR; Q8S9L0; -.
DR STRING; 3702.AT1G27370.1; -.
DR PaxDb; Q8S9L0; -.
DR PRIDE; Q8S9L0; -.
DR ProteomicsDB; 228457; -.
DR EnsemblPlants; AT1G27370.1; AT1G27370.1; AT1G27370.
DR EnsemblPlants; AT1G27370.2; AT1G27370.2; AT1G27370.
DR EnsemblPlants; AT1G27370.3; AT1G27370.3; AT1G27370.
DR EnsemblPlants; AT1G27370.4; AT1G27370.4; AT1G27370.
DR EnsemblPlants; AT1G27370.5; AT1G27370.5; AT1G27370.
DR EnsemblPlants; AT1G27370.7; AT1G27370.7; AT1G27370.
DR GeneID; 839626; -.
DR Gramene; AT1G27370.1; AT1G27370.1; AT1G27370.
DR Gramene; AT1G27370.2; AT1G27370.2; AT1G27370.
DR Gramene; AT1G27370.3; AT1G27370.3; AT1G27370.
DR Gramene; AT1G27370.4; AT1G27370.4; AT1G27370.
DR Gramene; AT1G27370.5; AT1G27370.5; AT1G27370.
DR Gramene; AT1G27370.7; AT1G27370.7; AT1G27370.
DR KEGG; ath:AT1G27370; -.
DR Araport; AT1G27370; -.
DR TAIR; locus:2016014; AT1G27370.
DR eggNOG; ENOG502QTXG; Eukaryota.
DR HOGENOM; CLU_026055_1_0_1; -.
DR InParanoid; Q8S9L0; -.
DR OrthoDB; 607491at2759; -.
DR PhylomeDB; Q8S9L0; -.
DR PRO; PR:Q8S9L0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8S9L0; baseline and differential.
DR Genevisible; Q8S9L0; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IPI:TAIR.
DR GO; GO:0010358; P:leaf shaping; IMP:TAIR.
DR GO; GO:0090356; P:negative regulation of auxin metabolic process; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.1100.10; -; 1.
DR InterPro; IPR004333; SBP_dom.
DR InterPro; IPR036893; SBP_sf.
DR InterPro; IPR044817; SPL.
DR PANTHER; PTHR31251; PTHR31251; 1.
DR Pfam; PF03110; SBP; 1.
DR SUPFAM; SSF103612; SSF103612; 1.
DR PROSITE; PS51141; ZF_SBP; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..396
FT /note="Squamosa promoter-binding-like protein 10"
FT /id="PRO_0000132731"
FT ZN_FING 173..250
FT /note="SBP-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT REGION 74..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 233..249
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255"
FT BINDING 176
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 181
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 198
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 201
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 217
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 220
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 224
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 236
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT CONFLICT 52
FT /note="G -> R (in Ref. 4; AAL75905)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 396 AA; 44159 MW; 7CC1CF18582695A9 CRC64;
MDCNMVSSFP WDWENLIMSN QSKTENEKKQ QSTEWEFEKG EGIESIVPDF LGFEKVSSGS
ATSFWHTAVS KSSQSTSINS SSPEDKRCNL ASQSSPGDSS SNIDFLQVKP STALEVPIAS
AESDLCLKLG KRTYSEEFWG RNNNDLSAVS MNLLTPSVVA RKKTKSCGQS MQVPRCQIDG
CELDLSSSKD YHRKHRVCET HSKCPKVVVS GLERRFCQQC SRFHAVSEFD EKKRSCRKRL
SHHNARRRKP QGVFPLNSER VFDRRQHTSM LWNGLSLNTR SEEKYTWGTT YETKPTQMES
GFTLSFQRGN GSEDQLFTGS TLSFSAFQTS GGFSAGKSNI QLPDKGVGEC SGGLHESHDF
YSALSLLSTT SDSQGIKHTP VAEPPPIFGT FPSHFI
