SPL12_ORYSJ
ID SPL12_ORYSJ Reviewed; 475 AA.
AC Q5Z818; B7ELT2;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Squamosa promoter-binding-like protein 12;
GN Name=SPL12; OrderedLocusNames=Os06g0703500, LOC_Os06g49010;
GN ORFNames=OJ1215_E11.11, OsJ_22552 {ECO:0000312|EMBL:EEE66315.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16861571; DOI=10.1104/pp.106.084475;
RA Xie K., Wu C., Xiong L.;
RT "Genomic organization, differential expression, and interaction of SQUAMOSA
RT promoter-binding-like transcription factors and microRNA156 in rice.";
RL Plant Physiol. 142:280-293(2006).
RN [7]
RP GENE FAMILY.
RX PubMed=17629421; DOI=10.1016/j.gene.2007.02.034;
RA Yang Z., Wang X., Gu S., Hu Z., Xu H., Xu C.;
RT "Comparative study of SBP-box gene family in Arabidopsis and rice.";
RL Gene 407:1-11(2008).
CC -!- FUNCTION: Trans-acting factor that binds specifically to the consensus
CC nucleotide sequence 5'-TNCGTACAA-3' (By similarity). May be involved in
CC panicle development. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in young panicles.
CC {ECO:0000269|PubMed:16861571}.
CC -!- INDUCTION: Negatively regulated by microRNAs miR156b and miR156h.
CC {ECO:0000305|PubMed:16861571}.
CC -!- DOMAIN: The SBP-type zinc finger is required for the binding to DNA.
CC {ECO:0000250}.
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DR EMBL; AP004324; BAD54038.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF20413.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS99371.1; -; Genomic_DNA.
DR EMBL; CM000143; EEE66315.1; -; Genomic_DNA.
DR EMBL; AK073179; BAG93329.1; -; mRNA.
DR EMBL; AK102136; BAG95406.1; -; mRNA.
DR RefSeq; XP_015643448.1; XM_015787962.1.
DR RefSeq; XP_015643449.1; XM_015787963.1.
DR RefSeq; XP_015643450.1; XM_015787964.1.
DR RefSeq; XP_015643451.1; XM_015787965.1.
DR RefSeq; XP_015643452.1; XM_015787966.1.
DR RefSeq; XP_015643453.1; XM_015787967.1.
DR RefSeq; XP_015643454.1; XM_015787968.1.
DR RefSeq; XP_015643455.1; XM_015787969.1.
DR RefSeq; XP_015643456.1; XM_015787970.1.
DR RefSeq; XP_015643457.1; XM_015787971.1.
DR RefSeq; XP_015643458.1; XM_015787972.1.
DR RefSeq; XP_015643459.1; XM_015787973.1.
DR RefSeq; XP_015643461.1; XM_015787975.1.
DR RefSeq; XP_015643462.1; XM_015787976.1.
DR AlphaFoldDB; Q5Z818; -.
DR SMR; Q5Z818; -.
DR STRING; 4530.OS06T0703500-02; -.
DR PaxDb; Q5Z818; -.
DR PRIDE; Q5Z818; -.
DR EnsemblPlants; Os06t0703500-01; Os06t0703500-01; Os06g0703500.
DR EnsemblPlants; Os06t0703500-02; Os06t0703500-02; Os06g0703500.
DR GeneID; 4341986; -.
DR Gramene; Os06t0703500-01; Os06t0703500-01; Os06g0703500.
DR Gramene; Os06t0703500-02; Os06t0703500-02; Os06g0703500.
DR KEGG; osa:4341986; -.
DR eggNOG; ENOG502QTXG; Eukaryota.
DR HOGENOM; CLU_026055_2_0_1; -.
DR InParanoid; Q5Z818; -.
DR OMA; ESMISFN; -.
DR OrthoDB; 607491at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000007752; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR ExpressionAtlas; Q5Z818; baseline and differential.
DR Genevisible; Q5Z818; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1100.10; -; 1.
DR InterPro; IPR004333; SBP_dom.
DR InterPro; IPR036893; SBP_sf.
DR InterPro; IPR044817; SPL.
DR PANTHER; PTHR31251; PTHR31251; 1.
DR Pfam; PF03110; SBP; 1.
DR SUPFAM; SSF103612; SSF103612; 1.
DR PROSITE; PS51141; ZF_SBP; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..475
FT /note="Squamosa promoter-binding-like protein 12"
FT /id="PRO_0000308238"
FT ZN_FING 177..254
FT /note="SBP-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT REGION 49..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 237..253
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255"
FT BINDING 180
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 185
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 202
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 205
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 221
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 224
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 228
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
FT BINDING 240
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00470"
SQ SEQUENCE 475 AA; 50743 MW; 31A1C193C754E72E CRC64;
MASFGMNWNQ KSPVFWDWEN PAPFGPNTME NPKSIPHPEP RGVVVAAANH GSTNSSGGTF
TSSSELANGS SKSSLSASFD SSSKLGNSLE FRFASVKGHG KNMCKDGEAG RVEDSGTSPA
VAVSHGEPVI GLKLGKRTYF ENVCGGQNVK SSSAASGVTC PSTVVKKMKV SQQSTQSSYC
QVEGCKVDLS SAREYHRKHK VCEAHSKAPK VIVSGLERRF CQQCSRFHGL AEFDQKKKSC
RRRLSDHNAR RRKPQQEAIS FGSSRLATMF YDARQQTDIY FGQSPFGQVR SNAISSCDNL
GGFKFTEAKL PWMKPMKTIG LEDLNFSTLQ MPGNVVSHTV HHHDFDGLIP FKGNTPKVLN
QGVDPACAVV SSNSNGAPDL RRALSLLSSD SWGPADVQAG SQVHPGGVMP PLAVAAATVT
APTNPVSVMH ALHPSTGGGG FWQDGDDPPP LDHASQAQAF MHPGNGSSSG YGHLH
