ID   SPL2A_BOVIN             Reviewed;         239 AA.
AC   P79124;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Short palate, lung and nasal epithelium carcinoma-associated protein 2A;
DE   AltName: Full=BSP30a;
DE   AltName: Full=Common salivary protein form a;
DE   Flags: Precursor;
GN   Name=SPLUNC2A; Synonyms=BSP30A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Holstein-Friesian; TISSUE=Parotid gland;
RX   PubMed=12427544; DOI=10.1016/s0167-4781(02)00508-0;
RA   Wheeler T.T., Haigh B.J., McCracken J.Y., Wilkins R.J., Morris C.A.,
RA   Grigor M.R.;
RT   "The BSP30 salivary proteins from cattle, LUNX/PLUNC and von Ebner's minor
RT   salivary gland protein are members of the PSP/LBP superfamily of
RT   proteins.";
RL   Biochim. Biophys. Acta 1579:92-100(2002).
RN   [2]
RP   SEQUENCE REVISION TO C-TERMINUS.
RA   Haigh B.J., Wilkins R.J., Wheeler T.T.;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Detected in salivary tissues: parotid,
CC       submandibular and sublingual glands.
CC   -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
CC       {ECO:0000305}.
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DR   EMBL; U79413; AAB38282.2; -; mRNA.
DR   RefSeq; NP_777228.2; NM_174803.3.
DR   AlphaFoldDB; P79124; -.
DR   SMR; P79124; -.
DR   STRING; 9913.ENSBTAP00000012052; -.
DR   PaxDb; P79124; -.
DR   PRIDE; P79124; -.
DR   GeneID; 286882; -.
DR   KEGG; bta:286882; -.
DR   CTD; 286882; -.
DR   eggNOG; ENOG502TE6F; Eukaryota.
DR   InParanoid; P79124; -.
DR   OrthoDB; 1389938at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030141; C:secretory granule; IBA:GO_Central.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IBA:GO_Central.
DR   InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR   InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR   Pfam; PF01273; LBP_BPI_CETP; 1.
DR   SUPFAM; SSF55394; SSF55394; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..239
FT                   /note="Short palate, lung and nasal epithelium carcinoma-
FT                   associated protein 2A"
FT                   /id="PRO_0000017182"
FT   DISULFID        166..209
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   239 AA;  26382 MW;  B380E11C5B5C2FE8 CRC64;
     MVQLWKLVLL CGLLAGTSES LLDIRGNDVL RRLISGLERG LGTFDSTIEI IFQNLKTELE
     SRCLNDVVEE TQQTENSLEG LISRIFQVVN RLTGVRIRNV QVPDITFEAT SENSADVSIP
     ITADVTVSLP LLGEIVKLDL NVDLQTSVSI ETDAETGDSR VVVGECPNNP ESISLTVLHR
     RPGLLNDVVD FGVNLVRQLV SSVVQHELCP RIRELLESLD TECIKKLIGE PQVTTQQEI