SPLR_NPVAC
ID SPLR_NPVAC Reviewed; 302 AA.
AC P23058;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1991, sequence version 1.
DT 29-SEP-2021, entry version 93.
DE RecName: Full=Spheroidin-like protein;
DE AltName: Full=37 kDa glycoprotein;
DE AltName: Full=Spindolin-like protein;
DE Flags: Precursor;
GN Name=SLP; Synonyms=GP37; ORFNames=ORF64;
OS Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=46015;
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=L1;
RX PubMed=2674327; DOI=10.1099/0022-1317-70-9-2449;
RA Wu J.G., Miller L.K.;
RT "Sequence, transcription and translation of a late gene of the Autographa
RT californica nuclear polyhedrosis virus encoding a 34.8K polypeptide.";
RL J. Gen. Virol. 70:2449-2459(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX PubMed=2243377; DOI=10.1128/jvi.64.12.5804-5811.1990;
RA Vialard J.E., Yuen L., Richardson C.D.;
RT "Identification and characterization of a baculovirus occlusion body
RT glycoprotein which resembles spheroidin, an entomopoxvirus protein.";
RL J. Virol. 64:5804-5811(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6;
RX PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT virus.";
RL Virology 202:586-605(1994).
CC -!- FUNCTION: Component of the virus occlusion bodies, which are large
CC proteinaceous structures (polyhedra), that protect the virus from the
CC outside environment for extended periods until they are ingested by
CC insect larvae. {ECO:0000269|PubMed:2243377}.
CC -!- SUBUNIT: Homodimer; disulfide-linked.
CC -!- SUBCELLULAR LOCATION: Host membrane. Note=Occlusion body. Associated
CC with the periphery of occlusion bodies and with the internal membranes
CC of infected cells.
CC -!- DEVELOPMENTAL STAGE: Very late phase of infection.
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DR EMBL; D00583; BAA00461.1; -; Genomic_DNA.
DR EMBL; L22858; AAA66694.1; -; Genomic_DNA.
DR PIR; A34036; WMNV34.
DR RefSeq; NP_054094.1; NC_001623.1.
DR SMR; P23058; -.
DR CAZy; AA10; Auxiliary Activities 10.
DR GeneID; 1403897; -.
DR KEGG; vg:1403897; -.
DR Proteomes; UP000008292; Genome.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0039679; C:viral occlusion body; IEA:UniProtKB-KW.
DR InterPro; IPR004302; Cellulose/chitin-bd_N.
DR InterPro; IPR014756; Ig_E-set.
DR Pfam; PF03067; LPMO_10; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Host membrane; Late protein; Membrane;
KW Reference proteome; Signal; Viral occlusion body.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..302
FT /note="Spheroidin-like protein"
FT /id="PRO_0000036744"
FT CARBOHYD 193
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 293
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 302 AA; 34798 MW; DB1FE1D3E7A1AC42 CRC64;
MIALLIALFA AIHAPAVRSH GYLSVPTARQ YKCFKDGNFY WPDNGDNIPD AACRNAYKSV
YYKYRALDLE SGAAASTAQY MFQQYMEYAA VAGPNYDDFD LIKQRVVPHT LCGAGSNDRN
SVFGDKSGMD EPFNNWRPNT LYLNRYQPVY QMNVHFCPTA IHEPSYFEVF ITKSNWDRRN
PITWNELEYI GGNDSNLIPN PGDSLCDNSL VYSIPVVIPY RSNQFVMYVR WQRIDPVGEG
FYNCADLVFE TLDDECRYAQ MAKVVRSQLQ KHKLDARIDH NDEESCWRAR KSNYSSFFNP
GF
