SPMA_BACSU
ID SPMA_BACSU Reviewed; 196 AA.
AC P35157;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Spore maturation protein A;
GN Name=spmA; Synonyms=ypuJ; OrderedLocusNames=BSU23180;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC 3610 / NRRL NRS-744 / VKM B-501;
RX PubMed=7934829; DOI=10.1111/j.1365-2958.1993.tb02670.x;
RA Sorokin A.V., Zumstein E., Azevedo V., Ehrlich S.D., Serror P.;
RT "The organization of the Bacillus subtilis 168 chromosome region between
RT the spoVA and serA genetic loci, based on sequence data.";
RL Mol. Microbiol. 10:385-395(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1548223; DOI=10.1128/jb.174.6.1717-1725.1992;
RA Buchanan C.E., Ling M.-L.;
RT "Isolation and sequence analysis of dacB, which encodes a sporulation-
RT specific penicillin-binding protein in Bacillus subtilis.";
RL J. Bacteriol. 174:1717-1725(1992).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP CHARACTERIZATION.
RX PubMed=7642500; DOI=10.1128/jb.177.16.4721-4729.1995;
RA Popham D.L., Illades-Auiar B., Setlow P.;
RT "The Bacillus subtilis dacB gene, encoding penicillin-binding protein 5*,
RT is part of a three-gene operon required for proper spore cortex synthesis
RT and spore core dehydration.";
RL J. Bacteriol. 177:4721-4729(1995).
CC -!- FUNCTION: Involved in spore core dehydration; might be involved in the
CC transport of something into or out of the forespore or could be
CC required for some modification of the cortex peptidoglycan structure.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=M84227; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; L09228; AAA67491.1; -; Genomic_DNA.
DR EMBL; M84227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL009126; CAB14250.1; -; Genomic_DNA.
DR PIR; S45553; S45553.
DR RefSeq; NP_390199.1; NC_000964.3.
DR RefSeq; WP_004398980.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; P35157; -.
DR STRING; 224308.BSU23180; -.
DR PaxDb; P35157; -.
DR PRIDE; P35157; -.
DR EnsemblBacteria; CAB14250; CAB14250; BSU_23180.
DR GeneID; 938954; -.
DR KEGG; bsu:BSU23180; -.
DR PATRIC; fig|224308.179.peg.2525; -.
DR eggNOG; COG2715; Bacteria.
DR InParanoid; P35157; -.
DR OMA; ASDAMCT; -.
DR PhylomeDB; P35157; -.
DR BioCyc; BSUB:BSU23180-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR InterPro; IPR011642; Gate_dom.
DR Pfam; PF07670; Gate; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Sporulation; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..196
FT /note="Spore maturation protein A"
FT /id="PRO_0000072129"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 196 AA; 21494 MW; 55ACE26CB7205992 CRC64;
MVNIIWVSLT VIGLVFAMCN GTLQDVNEAV FKGAKEAITI SFGLMSVLVF WLGLMKIAEQ
SGLLDIFSRM CRPFISKLFP DIPPDHPAMG YILSNLMANF FGLGNAATPL GIKAMEQMKK
LNGNRSEASR SMITFLAVNT SCITLIPTTV IAVRMAYSSK TPTDIVGPSI LATLISGIGA
IIIDRYFYYR RKKKGR
