ID   SPMI_PIG                Reviewed;         137 AA.
AC   Q28920;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Seminal plasma sperm motility inhibitor;
DE   Flags: Precursor;
GN   Name=SPMI;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Seminal vesicle;
RX   PubMed=7635190; DOI=10.1016/0014-5793(95)00701-a;
RA   Iwamoto T., Hiroaki H., Furuichi Y., Wada K., Satoh M., Satoh M., Osada T.,
RA   Gagnon C.;
RT   "Cloning of boar SPMI gene which is expressed specifically in seminal
RT   vesicle and codes for a sperm motility inhibitor protein.";
RL   FEBS Lett. 368:420-424(1995).
CC   -!- FUNCTION: Inhibitor of sperm motility.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Seminal plasma or sperm.
CC   -!- SIMILARITY: Belongs to the spermadhesin family. {ECO:0000305}.
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DR   EMBL; S80568; AAB35000.2; -; mRNA.
DR   PIR; S72508; S72508.
DR   STRING; 9823.ENSSSCP00000003222; -.
DR   PRIDE; Q28920; -.
DR   eggNOG; ENOG502TD48; Eukaryota.
DR   InParanoid; Q28920; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   CDD; cd00041; CUB; 1.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   InterPro; IPR000124; Spermadhesin.
DR   Pfam; PF00431; CUB; 1.
DR   SMART; SM00042; CUB; 1.
DR   SUPFAM; SSF49854; SSF49854; 1.
DR   PROSITE; PS01180; CUB; 1.
DR   PROSITE; PS00985; SPERMADHESIN_1; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Fertilization; Glycoprotein; Heparin-binding;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..137
FT                   /note="Seminal plasma sperm motility inhibitor"
FT                   /id="PRO_0000033190"
FT   DOMAIN          30..131
FT                   /note="CUB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00059"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        30..51
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00059"
SQ   SEQUENCE   137 AA;  15196 MW;  9DC107799A4C71EF CRC64;
     MKLGSAIPWA LLLSTXTLVS TAQNKGSDDC GGFLKNYSGW ISYYKALTTN CVWTIEMKPG
     HKIILQILPL NLWTIEMKLE VRDQRAGPDN FLKVCGGTTF VYQSSSNVAT VKYSRESHHP
     ASSFNVYFYG IPQGAKA