ID   SPO12_SCHPO             Reviewed;          90 AA.
AC   Q10189;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Mitosis-specific protein spo12;
GN   Name=spo12; ORFNames=SPAC3F10.15c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=11085271; DOI=10.1007/s004380000324;
RA   Samuel J.M., Fournier N., Simanis V., Millar J.B.A.;
RT   "spo12 is a multicopy suppressor of mcs3 that is periodically expressed in
RT   fission yeast mitosis.";
RL   Mol. Gen. Genet. 264:306-316(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Has a role in controlling mitotic cell cycle progression at
CC       the G2/M transition phase. {ECO:0000269|PubMed:11085271}.
CC   -!- SIMILARITY: To yeast SPO12. {ECO:0000305}.
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DR   EMBL; CU329670; CAA93313.1; -; Genomic_DNA.
DR   PIR; T38716; T38716.
DR   RefSeq; NP_593947.1; NM_001019374.2.
DR   AlphaFoldDB; Q10189; -.
DR   BioGRID; 279630; 19.
DR   STRING; 4896.SPAC3F10.15c.1; -.
DR   iPTMnet; Q10189; -.
DR   MaxQB; Q10189; -.
DR   PaxDb; Q10189; -.
DR   PRIDE; Q10189; -.
DR   EnsemblFungi; SPAC3F10.15c.1; SPAC3F10.15c.1:pep; SPAC3F10.15c.
DR   GeneID; 2543201; -.
DR   KEGG; spo:SPAC3F10.15c; -.
DR   PomBase; SPAC3F10.15c; spo12.
DR   VEuPathDB; FungiDB:SPAC3F10.15c; -.
DR   eggNOG; ENOG502SBH5; Eukaryota.
DR   HOGENOM; CLU_2442127_0_0_1; -.
DR   InParanoid; Q10189; -.
DR   OMA; AHKKKYY; -.
DR   PRO; PR:Q10189; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0031536; P:positive regulation of exit from mitosis; ISO:PomBase.
DR   InterPro; IPR007727; Spo12.
DR   Pfam; PF05032; Spo12; 1.
PE   4: Predicted;
KW   Cell cycle; Cell division; Mitosis; Reference proteome.
FT   CHAIN           1..90
FT                   /note="Mitosis-specific protein spo12"
FT                   /id="PRO_0000072132"
SQ   SEQUENCE   90 AA;  10130 MW;  806E188916937323 CRC64;
     MSETQADSIA KSSVETTIQP LHQESATLRQ QVLQKHELPK HALNVASPTD SLMSPCTAKL
     QAHKKKYYMK RKPPVMSLQN TLQSVQTEKE